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  4. Recombinant Human Beta-defensin 4A protein (DEFB4A) (Active)

Recombinant Human Beta-defensin 4A protein (DEFB4A) (Active)

In Stock
  • 中文名稱：
    Recombinant Human Beta-defensin 4A protein(DEFB4A) (Active)
  • 貨號：
    CSB-AP003041HU
  • 規(guī)格：
    ￥852
  • 圖片：
  • 其他：

產品詳情

  • 純度：
    >98% as determined by SDS-PAGE.
  • 內毒素：
    Less than 1.0 EU/μg as determined by LAL method.
  • 生物活性：
    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using immature human dendritic cells is in a concentration range of 10-100 ng/ml.
  • 基因名：
    DEFB4A
  • Uniprot No.：
  • 別名：
    BD 2; BD-2; BD2; beta 2; beta 2 Defensin; Beta defensin 2; Beta defensin 4B; Beta-defensin 2; Beta-defensin 4A; DEF B2; DEF B4; DEFB 102; DEFB 2; DEFB 4; DEFB102; DEFB2; DEFB2; formerly; DEFB4; DEFB4; formerly; DEFB4B; DEFB4P; Defensin; Defensin beta 2; Defensin; beta 4; Defensin; beta 4; pseudogene; Defensin; beta 4A; Defensin; beta 4B; Defensin; beta; 2; formerly; Defensin; beta; 4; formerly; DFB4A_HUMAN; HBD 2; hBD-2; HBD2; mBD-2; SAP 1; SAP1; Skin antimicrobial peptide 1; Skin-antimicrobial peptide 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 來源：
    E.Coli
  • 分子量：
    4.3 kDa
  • 表達區(qū)域：
    24-64aa
  • 氨基酸序列
    GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
  • 蛋白標簽：
    Tag-Free
  • 產品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    0.2 μm filtered 20 mM PB, pH 7.4, 130 mM NaCl ,lyophilized
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    5-10 business days
  • Datasheet & COA：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells.
  • 基因功能參考文獻：
    1. The encoded peptide has antimicrobial activity against E.coli, S. aureus, and P. aeruginosa. PMID: 9727055
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Beta-defensin family, LAP/TAP subfamily
  • 組織特異性：
    Expressed in the skin and respiratory tract.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2767

    OMIM: 602215

    KEGG: hsa:100289462

    STRING: 9606.ENSP00000424598

    UniGene: Hs.105924