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TNFSF13

TNFSF13,也稱為APRIL,是腫瘤壞死因子超家族的重要成員,它在淋巴組織、脾臟、骨髓等免疫相關(guān)組織中高表達(dá)。作為一個(gè)多肽,TNFSF13在體液免疫中發(fā)揮著調(diào)節(jié)B細(xì)胞激活和抗體產(chǎn)生的關(guān)鍵作用,通過與BCMA和TACI等受體相互作用,促進(jìn)B細(xì)胞的增殖和存活。TNFSF13重組蛋白是人工制備的,具有特定的生物學(xué)活性,廣泛應(yīng)用于科學(xué)研究,包括SDS-PAGE分析以及其他功能研究。這種重組蛋白在免疫調(diào)節(jié)和抗炎治療領(lǐng)域具有潛在的應(yīng)用價(jià)值,為開發(fā)新的免疫治療策略提供了可能。


熱銷產(chǎn)品

Recombinant Human Tumor necrosis factor ligand superfamily member 13 (TNFSF13) (Active) (CSB-MP023989HU)

驗(yàn)證數(shù)據(jù)

CSB-MP023989HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP023989HU

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human TNFSF13 protein at 2 μg/ml can bind Human TNFRSF17 protein (CSB-MP023974HU1-B). The EC50 is 0.8083-0.9391 ng/mL.

CSB-MP023989HU

Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis TNFRSF13B protein (CSB-MP6427MOV) at 2 μg/ml can bind Human TNFSF13 protein. The EC50 is 11.13-18.97 ng/mL.

TNFSF13 Antibody (CSB-PA023989ESR1HU)

驗(yàn)證數(shù)據(jù)

CSB-PA023989ESR1HU

Western blot
All lanes: Tumor necrosis factor ligand superfamily member 13 antibody at 10μg/ml + Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 28, 26, 25, 37, 23 kDa
Observed band size: 28 kDa

CSB-PA023989ESR1HU

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA023989ESR1HU at dilution of 1:100

CSB-PA023989ESR1HU

Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA023989ESR1HU at dilution of 1:100

TNFSF13 Antibodies

TNFSF13 for Homo sapiens (Human)

TNFSF13 Proteins

TNFSF13 Proteins for Homo sapiens (Human)

TNFSF13 ELISA Kit

TNFSF13 ELISA Kit for Homo sapiens (Human)