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ACAP2 Antibody

  • 中文名稱：
    ACAP2兔多克隆抗體
  • 貨號：
    CSB-PA001132GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ACAP 2 antibody; ACAP2 antibody; ACAP2_HUMAN antibody; ANK repeat and PH domain-containing protein 2 antibody; Arf GAP with coiled coil ANK repeat and PH domain containing protein 2 antibody; Arf GAP with coiled coil ANK repeat and PH domains 2 antibody; Arf-GAP with coiled-coil antibody; ArfGAP with coiled coil ankyrin repeat and PH domains 2 antibody; CENT B 2 antibody; Centaurin beta2 antibody; Centaurin-beta-2 antibody; CENTB 2 antibody; CENTB2 antibody; Cnt b2 antibody; Cnt-b2 antibody; Cntb2 antibody; KIAA0041 antibody; Similar to yeast ZINC FINGER PROTEIN GCS1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ACAP2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).
  • 基因功能參考文獻：
    1. The down-regulation of circRNA-ACAP2 promoted miR-21-5p expression, which further suppressed the transcription and translation of Tiam1. PMID: 30212824
    2. ACAP2 is a functional homolog of C. elegans CNT-1 and its inactivation or downregulation in human cells may contribute to cancer development PMID: 25853217
    3. ACAP2 has robust, constitutive Arf6 GAP activity in vivo, with little activity toward Arf1. PMID: 18003747
    4. Centaurin beta2/KIAA0041, is a member of the centaurin family of ADP-ribosylation factor directed GTPase-activating proteins. Binding of phosphoinositides to a pleckstrin homology domain may regulate subcellular localisation and activity. PMID: 11050434
  • 亞細胞定位：
    Endosome membrane; Peripheral membrane protein.
  • 組織特異性：
    Widely expressed. Highest level in lung.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16469

    OMIM: 607766

    KEGG: hsa:23527

    STRING: 9606.ENSP00000324287

    UniGene: Hs.593373