Acta1 Antibody
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中文名稱:Acta1兔多克隆抗體
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貨號(hào):CSB-PA00750E0Rb
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規(guī)格:¥440
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Mus musculus (Mouse) Acta1 Polyclonal antibody
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Uniprot No.:
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基因名:
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別名:Acta1 antibody; ActaActin antibody; alpha skeletal muscle antibody; Alpha-actin-1) [Cleaved into: Actin antibody; alpha skeletal muscle antibody; intermediate form] antibody
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宿主:Rabbit
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反應(yīng)種屬:Mouse, Rat, Zebrafish
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免疫原:Mouse Actin, alpha skeletal muscle (Native Protein)
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免疫原種屬:Mus musculus (Mouse)
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標(biāo)記方式:Non-conjugated
本頁(yè)面中的產(chǎn)品,Acta1 Antibody (CSB-PA00750E0Rb),的標(biāo)記方式是Non-conjugated。對(duì)于Acta1 Antibody,我們還提供其他標(biāo)記。見(jiàn)下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, WB
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推薦稀釋比:
Application Recommended Dilution WB 1:1000-1:5000 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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基因功能參考文獻(xiàn):
- alpha smooth muscle actin (alphaSMA) was identified as a marker of osteoprogenitor cells in bone and periodontium. PMID: 26721734
- WIP is a link between membrane lipid composition and actin cytoskeleton at dendritic spines. PMID: 24698977
- ACTA1(Asp286Gly) mouse model of nemaline myopathy provide evidence of impaired in vivo muscle function, altered muscle structure and disturbed energy metabolism. PMID: 23977274
- Combined MRI and (3)(1)P-MRS investigations of the ACTA1(H40Y) mouse model of nemaline myopathy show impaired muscle function and altered energy metabolism. PMID: 23613869
- Data indicate roles for linkers of nucleus to cytoskeleton (LINC) molecules nesprin2giant and nesprin3, which anchor actin cap fibers to the nucleus. PMID: 23336069
- Asp286Gly acts as a "poison-protein" and according to the computational analysis it modifies the actin-actin interface. This phenomenon is likely to prevent proper myosin cross-bridge binding. PMID: 23029319
- Data show that upon actin binding, the two domains of utrophin become dramatically separated and ordered, indicating a transition to a single open and extended conformation. PMID: 21768337
- Data indicated that CacyBP/SIP could simultaneously interact with tubulin and actin, suggesting that CacyBP/SIP might link actin and tubulin cytoskeletons. PMID: 20637809
- Results provide the genetic proof that platelet production from megakaryocytes strictly requires dynamic changes in the actin cytoskeleton. PMID: 20530287
- Data show that while increases in cardiac and vascular smooth-muscle actin can partially compensate for the lack of skeletal actin in null mice, this is not sufficient to support adequate skeletal muscle growth and/or function. PMID: 12138199
- alpha-skeletal-muscle actin mutations have roles in development of myopathies PMID: 15226407
- myotome pairs are transiently left-right asymmetric, with higher expression of alpha-skeletal actin and myosin light chain 3F (MLC3F) on the left side between embryonic day 9.5-10.25. PMID: 15499557
- K+-depolarization increased Tnni1 and Acta1 mRNA levels in both differentiated C2C12 and rat skeletal muscle cells in primary culture PMID: 17146758
- Myotubes are a suitable system to study the capacity of a mutant to incorporate into actin structures or to form or induce pathological changes. PMID: 17227580
- Val163Met mutation in alpha-skeletal actin can affect the dynamics of other actin isoforms and severely disrupt sarcomeric structure, processes that can contribute to muscle weakness. PMID: 17705262
- F- and G-actin concentrations in lamellipodia are about 500 microM & 150 microM, respectively. The excess of G-actin shows that the polymerization rate is not limited by diffusion & is tightly controlled by polymerization/depolymerization modulators. PMID: 19277198
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亞細(xì)胞定位:Cytoplasm, cytoskeleton.
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蛋白家族:Actin family
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數(shù)據(jù)庫(kù)鏈接:
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