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  4. BUD13 Antibody, HRP conjugated

BUD13 Antibody, HRP conjugated

  • 中文名稱：
    BUD13兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA863104LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) BUD13 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    BUD13
  • 別名：
    Bud13 antibody; BUD13 homolog (S. cerevisiae) antibody; BUD13 homolog antibody; BUD13_HUMAN antibody; Cwc26 antibody; FLJ27090 antibody; fSAP71 antibody; Functional spliceosome-associated protein 71 antibody; MGC13125 antibody; OTTHUMP00000042639 antibody; OTTHUMP00000042640 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human BUD13 homolog protein (132-233AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in pre-mRNA splicing as component of the activated spliceosome.
  • 基因功能參考文獻(xiàn)：
    1. Data concluded that novel mutations in BUD13 did not confer risk for MetS in our study population, but these mutations changed the level of metabolic complements. PMID: 28659142
    2. by an integrated analysis of the genotypes and the serum levels of APOA5, BUD13 and triglyceride, we observed that BUD13 was another potential mediator, besides APOA5, of the association between rs651821 and serum triglyceride. rs671 (ALDH2), an east Asian-specific common variant, was found to be associated with MetS (Pcombined = 9.7 x 10(-22) ) in Han Chinese PMID: 28371326
    3. When the inter-dependence between alleles was examined using conditional models, five loci on BUD13, ZNF259, and ApoA5 showed possible independent associations. PMID: 26634697
    4. Single nucleotide polymorphisms (Rs17119975) of BUD13 protein did not increase the risk of CHD in the Chinese population. PMID: 26397108
    5. Common SNPs within the BUD13-APOA5 gene region can effect triglyceride and LDL cholesterol response to statin therapy. PMID: 25900265
    6. Single nucleotide polymorphism bud13 gene is associated with hyperlipidaemia. PMID: 24780069
    7. Significant linkage disequilibria were noted among ZNF259, BUD13 and MLXIPL SNPs and serum lipid levels. PMID: 24989072

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  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    CWC26 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 28199

    KEGG: hsa:84811

    STRING: 9606.ENSP00000260210

    UniGene: Hs.437341