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CA5B Antibody

  • 中文名稱(chēng)：
    CA5B兔多克隆抗體
  • 貨號(hào)：
    CSB-PA039070
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from NIH/3T3 cells, using CA5B antibody.
    • Immunofluorescence analysis of MCF-7 cells, using CA5B antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) CA5B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CA5B
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from internal of Human CA5B.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類(lèi)型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC,IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:200
    IF 1:100-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Reversible hydration of carbon dioxide.
  • 基因功能參考文獻(xiàn)：
    1. In 10 of 96 patients, mutations in CA5A were identified on both alleles but none in CA5B. Exhibiting decreased enzyme activity or thermal stability, all CAVA mutations were proven to cause disease, whereas the three variants showed no relevant effect PMID: 26913920
    2. activators enhanced kcat, with no effect on KM, favoring the RDS in the catalytic cycle; the activation pattern of the two mitochondrial isoforms is very different from each other and as compared to those of the cytosolic isoforms hCA I and II. PMID: 17174092
  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    Alpha-carbonic anhydrase family
  • 組織特異性：
    Strongest expression in heart, pancreas, kidney, placenta, lung, and skeletal muscle. Not expressed in liver.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 1378

    OMIM: 300230

    KEGG: hsa:11238

    STRING: 9606.ENSP00000314099

    UniGene: Hs.653287