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CSN2 Antibody, HRP conjugated

  • 中文名稱：
    CSN2兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA006063LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) CSN2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CSN2
  • 別名：
    Beta-casein antibody; CASB antibody; CASB_HUMAN antibody; Casein beta antibody; CSN 2 antibody; Csn2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Beta-casein protein (16-226AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Important role in determination of the surface properties of the casein micelles.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest that neurogenesis in neuronal stem cells is differentially affected by human and bovine beta-casein-derived opioid peptides BCM7 and BCM9; such neurogenic changes are accompanied by changes in glutathione/glutathione disulfide ratio and in S-adenosylmethionine/S-adenosylhomocysteine ratio, indicative of changes in redox and methylation states (including DNA methylation). PMID: 27611101
    2. Exogenous 5-HT decreased beta-casein expression in MCF-12A human mammary epithelial cells and was responsible for inhibiting phosphorylation of STAT5, resulting in a decline in lactational function. PMID: 25087955
    3. The acidic fragment of human Abeta (Abeta1-11) and a phosphorylated fragment of beta-Casein induced tau fibrillization in vitro. PMID: 24364857
    4. Milk congestion gives rise to higher levels of beta-casomorphin-8 in milk and plasma than in lactating women without problems. PMID: 24189037
    5. derivatives of peptide fragment (54-59) exhibit immunosuppressant activity PMID: 19463972
    6. New functions of lactoferrin and beta-casein in mammalian milk as cysteine protease inhibitors. They might play a role in antiseptic and antiinfectious functions due to cysteine protease inhibition of bacteria and viruses. PMID: 12788072
    7. The RCM-kappa does form concentration-dependent micelles. Also, beta-CN phosphorylation level influences micelle formation. Complexes were low-temperature reversible and RCM-kappa fibrils were seen. PMID: 16947075
    8. a negative cross talk between PR and Stat5a/GR may contribute to the physiological role of progesterone to repress lactogenic hormone induction of the beta-casein gene PMID: 16973758

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  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Beta-casein family
  • 組織特異性：
    Mammary gland specific. Secreted in milk.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 2447

    OMIM: 115460

    KEGG: hsa:1447

    STRING: 9606.ENSP00000341030

    UniGene: Hs.2242