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DEPP1 Antibody, Biotin conjugated

  • 中文名稱(chēng)：
    DEPP1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA865135LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) DEPP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DEPP1
  • 別名：
    Decidual protein induced by progesterone antibody; Depp antibody; DEPP_HUMAN antibody; Fasting-induced gene protein antibody; FIG antibody; Protein DEPP antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protein DEPP1 protein (57-174AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
  • 基因功能參考文獻(xiàn)：
    1. Knockdown of DEPP prevented the primary and secondary reactive oxygen species wave during FOXO3 activation. PMID: 25261981
    2. C10orf10 expression is frequently decreased in breast cancer tissues and is associated with shorter survival times. PMID: 24936657
    3. DEPP is regulated at the level of transcription by FoxO in human vascular endothelial cells PMID: 21510935
    4. DEPP is a novel insulin-regulatory molecule expressed abundantly in insulin-sensitive tissues including white adipose tissue and liver. PMID: 19937567
    5. Expressed in endothelial cells of peripheral tissues, but not in atrial or ventricular endocardial cells of the heart, unexpected degree of molecular heterogeneity among arterial endothelial cells, up-regulated in subsets of endothelial cells. PMID: 15977181
    6. Depp modulates the effects of progesterone during decidualization and in the decidua by affecting gene expression. PMID: 16123073

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  • 亞細(xì)胞定位：
    Cytoplasm. Peroxisome. Mitochondrion.
  • 組織特異性：
    Expressed in various tissues, including pancreas, placenta, ovary, testis and kidney.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 23355

    OMIM: 611309

    KEGG: hsa:11067

    STRING: 9606.ENSP00000298295

    UniGene: Hs.93675