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  4. DMKN Antibody

DMKN Antibody

  • 中文名稱：
    DMKN兔多克隆抗體
  • 貨號：
    CSB-PA006965GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    DMKN
  • 別名：
    Dermokine antibody; DMKN antibody; DMKN_HUMAN antibody; Epidermis-specific secreted protein SK30/SK89 antibody; FLJ79374 antibody; UNQ729 antibody; UNQ729/PRO1411 antibody; ZD52F10 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human DMKN
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May act as a soluble regulator of keratinocyte differentiation.
  • 基因功能參考文獻(xiàn)：
    1. we showed that DMKN loss of function in Patu-8988 and PANC-1 pancreatic cancer cell lines resulted in reduced phosphorylation of STAT3.these data suggested that DMKN could be a potential prognostic biomarker and therapeutic target in pancreatic cancer. PMID: 28795470
    2. These results suggest that dermokine-beta delays early cutaneous wound healing in part by inhibiting expression of CXC chemokines containing the ERL-sequence motif. PMID: 23428944
    3. Serum DK is a potential biomarker in intraductal papillary mucinous neoplasm and invasive ductal carcinoma, when used in combination with conventional biomarkers. PMID: 23060565
    4. Dermokine-beta impairs ERK signaling through direct binding to GRP78 PMID: 22735594
    5. Dmkndelta activates Rab5 function and thus is involved in the early endosomal trafficking. PMID: 21423773
    6. Analysis of alternative spliced transcripts produced from the dermokine gene. PMID: 16374476
    7. Dermokine gene is expressed in epithelial tissues other than the skin and this expression is transcriptionally and posttranscriptionally complex. PMID: 17380110

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  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Dermokine family
  • 組織特異性：
    Expressed in epidermis; in the spinous and granular layers and in placenta. Also found in the epithelia of the small intestine, macrophages of the lung and endothelial cells of the lung. Isoform 15 is expressed in epidermis and placenta. Isoform 1 is expr
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25063

    KEGG: hsa:93099

    STRING: 9606.ENSP00000342012

    UniGene: Hs.417795