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LRCH1 Antibody

  • 中文名稱：
    LRCH1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA897471LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: LRCH1 antibody at 15µg/ml + Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 81, 78, 85 kDa
      Observed band size: 81 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA897471LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA897471LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) LRCH1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LRCH1
  • 別名：
    LRCH1 antibody; CHDC1 antibody; KIAA1016 antibody; Leucine-rich repeat and calponin homology domain-containing protein 1 antibody; Calponin homology domain-containing protein 1 antibody; Neuronal protein 81 antibody; NP81 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Leucine-rich repeat and calponin homology domain-containing protein 1 protein (1-105AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，LRCH1 Antibody (CSB-PA897471LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于LRCH1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA897471LB01HU LRCH1 Antibody, HRP conjugated ELISA
    FITC CSB-PA897471LC01HU LRCH1 Antibody, FITC conjugated
    Biotin CSB-PA897471LD01HU LRCH1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration.
  • 基因功能參考文獻(xiàn)：
    1. In the analysis of hip osteoarthritis cases with superior maximum joint space narrowing (JSN) versus cases with non-superior maximum JSN we detected association with a variant in the LRCH1 gene. PMID: 27974301
    2. Letter: Did not observe an association between LRCH-1 SNPs and knee osteoarthritis. PMID: 22325041
    3. A genetic variant in LRCH1 was consistently associated with knee osteoarthritis in 3 samples from 2 populations. PMID: 16447229
    4. results suggest that there is no association between LRCH1 and knee osteoarthritis susceptibility PMID: 18049793
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20309

    OMIM: 610368

    KEGG: hsa:23143

    STRING: 9606.ENSP00000374447

    UniGene: Hs.507971