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  4. OSGIN1 Antibody

OSGIN1 Antibody

  • 中文名稱：
    OSGIN1兔多克隆抗體
  • 貨號：
    CSB-PA017258GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    OSGIN1
  • 別名：
    OSGIN1 antibody; BDGI antibody; OKL38 antibody; Oxidative stress-induced growth inhibitor 1 antibody; Bone marrow stromal cell-derived growth inhibitor antibody; BMSC-derived growth inhibitor antibody; Ovary antibody; kidney and liver protein 38 antibody; huOKL38 antibody; Pregnancy-induced growth inhibitor OKL38 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human OSGIN1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulates the differentiation and proliferation through the regulation of cell death.
  • 基因功能參考文獻：
    1. The results support the concept that smoking-induced upregulation of OSGIN1 is one link between smoking-induced stress and enhanced-autophagy in the human airway epithelium. PMID: 28548877
    2. miR-320a has a role in modulating the induction of HO-1, GCLM and OKL38 by oxidized phospholipids in endothelial cells PMID: 24786516
    3. Identify OSGIN1 as a tumor suppressor that is down-regulated or altered in human hepatocellular carcinoma. PMID: 24417816
    4. Data suggest that OKL38 regulates mitochondria morphology and functions during apoptosis together with p53. PMID: 22912861
    5. Expression in cultured tumor cells resulted in growth inhibition and cell death. PMID: 14570898
    6. BDGI (Bone marrow stromal cell-derived growth inhibitor) inhibits growth and migration of breast cancer cells via induction of cell cycle arrest and apoptosis [BDGI] PMID: 15569677
    7. The 5'UTRs of OKL38 might play an important role in downregulation of its protein and the absence of OKL38 could lead to the development or progression of hepatocellular carcinoma. PMID: 16924236
    8. identify OKL38 as a novel p53 target gene that is regulated by Peptidylarginine deiminase 4 and plays a role in apoptosis PMID: 18499678

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  • 蛋白家族：
    OKL38 family
  • 組織特異性：
    Ubiquitous. Highest expression in the ovary, testis, kidney, skeletal muscle and liver. Weakly expressed in spleen, heart, kidney, and pancreas. Highly expressed in tumor cells (at protein level).
  • 數據庫鏈接：

    HGNC: 30093

    OMIM: 607975

    KEGG: hsa:29948

    UniGene: Hs.128055