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PPP1R14D Antibody

  • 中文名稱(chēng)：
    PPP1R14D兔多克隆抗體
  • 貨號(hào)：
    CSB-PA003840
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COLO205 cells using PPP1R14D Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    PPP1R14D
  • 別名：
    PPP1R14D antibody; GBPI antibody; Protein phosphatase 1 regulatory subunit 14D antibody; Gastrointestinal and brain-specific PP1-inhibitory protein 1 antibody; GBPI-1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PPP1R14D.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
  • 基因功能參考文獻(xiàn)：
    1. A gastrointestinal- and brain-specific PP1 inhibitory protein (GBPI-1)is activated by PKC phosphorylation. A longer GBPI-2 splice variant mRNA is found in testes. PMID: 12974676
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    PP1 inhibitor family
  • 組織特異性：
    Detected in colon, intestine, kidney and brain cortex.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 14953

    OMIM: 613256

    KEGG: hsa:54866

    STRING: 9606.ENSP00000398342

    UniGene: Hs.192927