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SHC2 Antibody

  • 中文名稱：
    SHC2兔多克隆抗體
  • 貨號：
    CSB-PA008569
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    SHC2 antibody; SCK antibody; SHCB antibody; SHC-transforming protein 2 antibody; Protein Sck antibody; SHC-transforming protein B antibody; Src homology 2 domain-containing-transforming protein C2 antibody; SH2 domain protein C2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Sck.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
  • 基因功能參考文獻：
    1. Sck was identified as a novel molecule indispensable for CD95's activation of the PI3K and MAPK pathways and induction of cell cycle progression in pancreatic ductal adenocarcinoma. PMID: 25613377
    2. SHC2 gene deletions underlie few, if any, cases of well-characterized multiple system atrophy in the US population. PMID: 24170347
    3. Data show that copy number loss of SHC2 strongly indicates a causal link to multiple system atrophy. PMID: 21658278
  • 組織特異性：
    Expressed in brain. Expressed at high level in the hypothalamus and at low level in the caudate nucleus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29869

    OMIM: 605217

    KEGG: hsa:25759

    STRING: 9606.ENSP00000264554

    UniGene: Hs.30965