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UNC45B Antibody, FITC conjugated

  • 中文名稱：
    UNC45B兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA812884LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) UNC45B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    UNC45B
  • 別名：
    Cardiomyopathy associated 4 antibody; CMYA4 antibody; FLJ38610 antibody; MGC119540 antibody; MGC119541 antibody; OTTHUMP00000163855 antibody; Protein unc 45 homolog B antibody; Protein unc-45 homolog B antibody; SMUNC45 antibody; Striated muscle UNC45 antibody; UN45B_HUMAN antibody; Unc 45 homolog B (C. elegans) antibody; Unc 45 homolog B antibody; UNC 45B antibody; UNC-45B antibody; UNC45 antibody; UNC45B antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein unc-45 homolog B protein (602-710AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
  • 基因功能參考文獻：
    1. We have characterized a human UNC45B mutation in a Danish family with autosomal dominant cataract developing in early childhood. PMID: 24549050
    2. temperature-dependent structural changes in the UCS chaperone domain of UNC-45B that occur within a physiologically relevant heat-shock range. PMID: 25436418
  • 相關疾病：
    Cataract 43 (CTRCT43)
  • 亞細胞定位：
    Cytoplasm, cytosol.
  • 組織特異性：
    Expressed in eye lens tissues.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 14304

    OMIM: 611220

    KEGG: hsa:146862

    STRING: 9606.ENSP00000268876

    UniGene: Hs.379636