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UXS1 Antibody, Biotin conjugated

  • 中文名稱：
    UXS1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA822754LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) UXS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    UXS1
  • 別名：
    UXS1 antibody; UNQ2538/PRO6079 antibody; UDP-glucuronic acid decarboxylase 1 antibody; EC 4.1.1.35 antibody; UDP-glucuronate decarboxylase 1 antibody; UGD antibody; UXS-1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human UDP-glucuronic acid decarboxylase 1 protein (201-420AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
  • 基因功能參考文獻(xiàn)：
    1. The persistence of a latent hexamer-building interface in the human enzyme suggests that the ancestral UXS may have been a hexamer. PMID: 25521717
    2. hUXS forms a tetramer in solution that is important for activity. The higher activity of the tetramer coupled with the relative instability of the dimeric complex suggests that an association-dissociation mechanism may regulate hUXS activity. PMID: 23656592
    3. UDP-glucuronate decarboxylase, a key enzyme in proteoglycan synthesis: cloning, characterization, and localization. PMID: 11877387
    4. Complementation was achieved by expression of a cytoplasmic variant of UDP-xylose Synthase, which proves the existence of a functional Golgi UDP-xylose transporter[UDP-xylose Synthase] PMID: 19028698
  • 亞細(xì)胞定位：
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    NAD(P)-dependent epimerase/dehydratase family, UDP-glucuronic acid decarboxylase subfamily
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17729

    OMIM: 609749

    KEGG: hsa:80146

    STRING: 9606.ENSP00000387019

    UniGene: Hs.469561