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  4. ZNF346 Antibody

ZNF346 Antibody

  • 中文名稱：
    ZNF346兔多克隆抗體
  • 貨號：
    CSB-PA026691ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA026691ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA026691ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA026691ESR1HU at dilution of 1:100
    • Immunoprecipitating ZNF346 in HepG2 whole cell lysate
      Lane 1: Rabbit control IgG (1µg) instead of CSB-PA026691ESR1HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the secondary antibody (1/50000)
      Lane 2: CSB-PA026691ESR1HU (4µg) + HepG2 whole cell lysate (500µg)
      Lane 3: HepG2 whole cell lysate (20µg)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ZNF346 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZNF346
  • 別名：
    DKFZp547M223 antibody; Double stranded RNA binding zinc finger protein antibody; Double stranded RNA binding zinc finger protein JAZ antibody; JAZ antibody; Just another zinc finger protein antibody; Zfp346 antibody; Zinc finger protein 346 antibody; ZN346_HUMAN antibody; Znf346 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Zinc finger protein 346 protein (1-294AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IP
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity. May bind to specific miRNA hairpins.
  • 基因功能參考文獻(xiàn)：
    1. JAZ directly binds E2F1 in vitro in a dsRNA-independent manner, and JAZ's dsRNA binding ZF domains, which are necessary for localizing JAZ to the nucleus, are required for repression of transcriptional activity in vivo. PMID: 21715977
    2. JAZ is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism PMID: 15254228
  • 亞細(xì)胞定位：
    Nucleus, nucleolus. Cytoplasm. Note=Nuclear at steady state, primarily in the nucleolus. Shuttles between the nucleus and cytoplasm when associated with XPO5.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16403

    OMIM: 605308

    KEGG: hsa:23567

    STRING: 9606.ENSP00000350869

    UniGene: Hs.484259