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  4. Recombinant Rat Cytochrome c oxidase subunit 6B1 (Cox6b1)

Recombinant Rat Cytochrome c oxidase subunit 6B1 (Cox6b1)

  • 中文名稱：
    Recombinant Rat Cytochrome c oxidase subunit 6B1(Cox6b1)
  • 貨號：
    005850RA
  • 規(guī)格：
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Cox6b1; Cox6bCytochrome c oxidase subunit 6B1; Cytochrome c oxidase subunit VIb isoform 1; COX VIb-1; Fragment
  • 免疫原種屬：
    Rattus norvegicus (Rat)
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 應(yīng)用說明：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 儲存條件：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
  • 蛋白家族：
    Cytochrome c oxidase subunit 6B family