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  4. Recombinant Chicken Vascular endothelial growth factor A (VEGFA)

Recombinant Chicken Vascular endothelial growth factor A (VEGFA)

  • 中文名稱：
    雞VEGFA重組蛋白
  • 貨號：
    025833CH
  • 規(guī)格：
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    VEGFA; VEGF; Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF
  • 免疫原種屬：
    Gallus gallus (Chicken)
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 應(yīng)用說明：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 儲存條件：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin.
  • 基因功能參考文獻(xiàn)：
    1. BFGF or VEGF gene therapy corrects insufficiency in the intrinsic healing capacity of tendons. PMID: 26865366
    2. VEGF expression in hyperoxia did not differ from normoxia on D16, yet, was actually approximately 75% higher in hyperoxia than in normoxia on day 18 PMID: 26300121
    3. VEGF-A protein was decreased in cadmium treated extraembryonic membranes. PMID: 26367766
    4. The results demonstrate that Vegf signaling could provide important insights into the complex relationship between bone and vasculature during intramembranous bone development. PMID: 26210172
    5. These data suggest that in ovo leptin administration affects angiogenesis and embryo growth in female chicken embryos, probably through STAT3-mediated VEGF/nitric oxide pathways. PMID: 22417645
    6. Homocysteine exposure causes impaired early extra embryonic vascular development, shown by altered composition of the vascular beds as well as reduced expression of VEGF-A and VEGFR-2. PMID: 22085786
    7. Decrease in VEGF expression induces intussusceptive vascular pruning. PMID: 21921259
    8. Short-term hypoxia transiently up-regulated VEGF146 1.5-fold at day 16 (p < 0.05). A similar trend was observed for VEGF122 (p = 0.058) and VEGF190 (p = 0.08), while no differences were present at day 19. PMID: 19864924
    9. VEGF upregulates heme oxygenase-1 protein expression in vivo in chicken embryo chorioallantoic membranes by a mechanism dependent on an increase in cytosolic calcium levels and activation of protein kinase C. PMID: 12788823
    10. VEGF regulates interaction of pericytes and endothelial cells during vasculogenesis and experimental angiogenesis PMID: 15108306
    11. VEGF signals increases progenitor cell proliferation and decreases retinal ganglion cell genesis PMID: 16672338
    12. VEGF genes and proteins are expressed at high or moderately high levels in healing tendon PMID: 19084187

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  • 蛋白家族：
    PDGF/VEGF growth factor family
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