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  4. GPR20 Recombinant Monoclonal Antibody

GPR20 Recombinant Monoclonal Antibody

  • 中文名稱：
    GPR20 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA860774MA1HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • The Binding Activity of Macaca fascicularis GPR20 with Anti-GPR20 recombinant antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis GPR20(CSB-MP5431MOV?) at 10 μg/mL can bind Anti-GPR20 recombinant antibody. The EC50 is 3.549 - 6.542 ng/mL.
    • The Binding Activity of Human GPR20 with Anti-GPR20 recombinant antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GPR20(CSB-MP860774HU) at 10 μg/mL can bind Anti-GPR20 recombinant antibody. The EC50 is 2.431 - 3.239 ng/mL.
    • The purity of GPR20 was greater than 95% as determined by SEC-HPLC
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CSB-RA860774MA1HU GPR20重組單克隆抗體是針對G蛋白偶聯(lián)受體20（GPR20）開發(fā)的高特異性檢測工具，適用于ELISA實(shí)驗(yàn)體系。該抗體經(jīng)重組表達(dá)技術(shù)制備，具有批次間高度一致性，在1:5000至1:50000稀釋范圍內(nèi)展現(xiàn)優(yōu)異的檢測靈敏度。GPR20作為孤兒受體在胃腸道間質(zhì)瘤等腫瘤細(xì)胞中呈現(xiàn)異常表達(dá)特征，本產(chǎn)品可通過抗原-抗體特異性結(jié)合實(shí)現(xiàn)對目標(biāo)蛋白的定量檢測，為研究GPR20在細(xì)胞信號轉(zhuǎn)導(dǎo)、腫瘤微環(huán)境調(diào)控中的功能機(jī)制提供可靠工具?？蒲腥藛T可將其應(yīng)用于體外培養(yǎng)細(xì)胞的蛋白表達(dá)水平分析、疾病相關(guān)分子通路研究及靶向治療基礎(chǔ)研究等實(shí)驗(yàn)場景，特別推薦用于胃腸道腫瘤模型構(gòu)建、受體功能驗(yàn)證等前沿研究領(lǐng)域。
  • Uniprot No.：
  • 基因名：
  • 別名：
    G protein coupled receptor 20 antibody; G-protein coupled receptor 20 antibody; Gpr20 antibody; GPR20_HUMAN antibody
  • 反應(yīng)種屬：
    Human, Macaca fascicularis
  • 免疫原：
    Recombinant Human GPR20 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    hIgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    2C1
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:5000-1:50000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP.
  • 基因功能參考文獻(xiàn)：
    1. GPR20 constitutively activates G(i) proteins without ligand stimulation PMID: 18347022
  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Ubiquitous with highest levels in intestinal tissues. In the brain detected in thalamus, putamen, and caudate, but not in frontal cortex, pons and hypothalamus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4475

    OMIM: 601908

    KEGG: hsa:2843

    STRING: 9606.ENSP00000366970

    UniGene: Hs.152432