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  4. Recombinant Acinetobacter baumannii Outer membrane protein Omp38 (omp38)

Recombinant Acinetobacter baumannii Outer membrane protein Omp38 (omp38)

In Stock
  • 中文名稱：
    Recombinant Acinetobacter baumannii Outer membrane protein Omp38(omp38)
  • 貨號(hào)：
    CSB-YP387720AUD
  • 規(guī)格：
    ￥2616
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    omp38
  • Uniprot No.：
  • 別名：
    omp38; A1S_2840; Outer membrane protein Omp38
  • 種屬：
    Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)
  • 蛋白長度：
    Full Length of Mature Protein
  • 來源：
    Yeast
  • 分子量：
    38.5kDa
  • 表達(dá)區(qū)域：
    20-356aa
  • 氨基酸序列
    ANAGVTVTPLLLGYTFQDSQHNNGGKDGNLTNGPELQDDLFVGAALGIELTPWLGFEAEYNQVKGDVDGASAGAEYKQKQINGNFYVTSDLITKNYDSKIKPYVLLGAGHYKYDFDGVNRGTRGTSEEGTLGNAGVGAFWRLNDALSLRTEARATYNADEEFWNYTALAGLNVVLGGHLKPAAPVVEVAPVEPTPVTPQPQELTEDLNMELRVFFDTNKSNIKDQYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSRTVVVQPGQEAAAPAAAQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產(chǎn)品描述：

    A truncated version of Acinetobacter baumannii outer membrane protein Omp38 lacking the 1-19 amino-acid signal peptide of the C-terminus and carrying a 6xHis-tag at the N-terminus was produced in the yeast. The resulting protein is a full-length of mature Omp38 protein. It contains aa of 20-356 of the Acinetobacter baumannii Omp38 protein. It was purified by SDS-PAGE and reached up to 90% in purity. On the reducing SDS-PAEG gel, this Omp38 protein migrated on the molecular weight band of about 40 kDa. The result is slightly higher than that of the calculated one due to glycosylation. This recombinant Omp38 protein may be used to generate specific antibodies against Omp38 or in the studies of Acinetobacter baumannii infections.

    The Acinetobacter baumannii outer membrane protein Omp38, also known as OmpA, is the most abundant surface protein that is responsible for the viral pathogenicity. As a virulence factor, Omp38 is involved in the modulation of adhesion, aggressiveness, and biofilm formation of Acinetobacter baumannii, antibiotic resistance, and the immune reaction of the host. Omp38 has been described as a powerful immunogen to trigger immune responses. It is a potential therapeutic target for the treatment of Acinetobacter baumannii infections.

  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor).
  • 亞細(xì)胞定位：
    Cell outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    OmpA family
  • 數(shù)據(jù)庫鏈接：

    KEGG: acb:A1S_2840