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  4. Recombinant Arabidopsis thaliana ATP-dependent DNA helicase Q-like 4A (RECQL4A), partial

Recombinant Arabidopsis thaliana ATP-dependent DNA helicase Q-like 4A (RECQL4A), partial

  • 中文名稱：
    擬南芥RECQL4A重組蛋白
  • 貨號：
    CSB-YP810545DOA
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    擬南芥RECQL4A重組蛋白
  • 貨號：
    CSB-EP810545DOA
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    擬南芥RECQL4A重組蛋白
  • 貨號：
    CSB-EP810545DOA-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    擬南芥RECQL4A重組蛋白
  • 貨號：
    CSB-BP810545DOA
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    擬南芥RECQL4A重組蛋白
  • 貨號：
    CSB-MP810545DOA
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    RECQL4A
  • Uniprot No.：
  • 別名：
    RECQL4A; RECQ4A; RQL4A; SGS1; At1g10930; T19D16.15; ATP-dependent DNA helicase Q-like 4A; EC 3.6.4.12; RecQ-like protein 4A; AtRecQ4A; AtRecQl4A; SGS1-like protein; AtSGS1
  • 種屬：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    3'-5' DNA helicase involved in DNA repair. Required for the maintenance of genome stability by modulation of the DNA damage response and repression of crossovers. Confers resistance to genotoxic stress. Suppresses spontaneous homologous recombination (HR) events in somatic cells together with its partners RMI1 and TOP3A. Contributes to the maintenance of chromosome integrity during meiosis. Involved in the removal of telomeric bridges that appear to arise during meiotic recombination. Required to resolve or dissolve MSH4-dependent telomeric associations. Does not seem required for chiasma formation.
  • 基因功能參考文獻(xiàn)：
    1. The N-terminus of RECQ4A was determined to be required for its specific functions in DNA repair and recombination. PMID: 24174542
    2. Pollen viability decreased in Atrecq4A, resulting in a reduction in fertility.Immunolocalization confirmed the association of AtRECQ4A with the telomeres during prophase I. PMID: 21265901
    3. RECQ4A and MUS81 define RAD5A-independent pathways of DNA repair. RAD5A and RECQ4A act through two independent pathways for intrastrand cross-link DNA repair. RECQ4A and MUS81 act in parallel pathways to resolve replication-associated DNA intermediates. PMID: 20971895
    4. Roles for Arabidopsis RecQl4A in maintenance of genome stability by modulation of the DNA damage response and suppression of HR are reported. PMID: 16146519
  • 亞細(xì)胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    Helicase family, RecQ subfamily
  • 組織特異性：
    Expressed in roots, seedlings, young leaves, shoots, shoot apical mersitem, inflorescences, flowers, siliques and seeds.
  • 數(shù)據(jù)庫鏈接：

    KEGG: ath:AT1G10930

    STRING: 3702.AT1G10930.1

    UniGene: At.10177