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  4. Recombinant Bovine Alpha-S1-casein (CSN1S1)

Recombinant Bovine Alpha-S1-casein (CSN1S1)

In Stock
  • 貨號：
    CSB-EP006060BO
  • 規(guī)格：
    ￥1836
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    CSN1S1
  • Uniprot No.：
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Full Length of Mature Protein
  • 來源：
    E.coli
  • 分子量：
    30.4 kDa
  • 表達區(qū)域：
    16-214aa
  • 氨基酸序列
    RPKHPIKHQGLPQEVLNENLLRFFVAPFPEVFGKEKVNELSKDIGSESTEDQAMEDIKQMEAESISSSEEIVPNSVEQKHIQKEDVPSERYLGYLEQLLRLKKYKVPQLEIVPNSAEERLHSMKEGIHAQQKEPMIGVNQELAYFYPELFRQFYQLDAYPSGAWYYVPLGTQYTDAPSFSDIPNPIGSENSEKTTMPLW
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Important role in the capacity of milk to transport calcium phosphate.; Antioxidant peptide has 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity.
  • 基因功能參考文獻：
    1. There were no associations between x genotype and fertility related traits in this study. PMID: 27065254
    2. The results give insight in phosphorylation of alpha(S1)-CN-8P and alpha(S1)-CN-9P, which seem to be regulated by a different set of genes. PMID: 25200775
    3. Report proteomic detection of bovine alpha-S1-casein in term and preterm human colostrum. PMID: 23755758
    4. Data indicate that the pepsin-pancreatin digest of alphaS-Casein exhibited anxiolytic-like activity. PMID: 23580614
    5. The genetic effects of thyroglobulin and casein alpha s1 alpha in the body fat distribution of cattle are reported. PMID: 23148258
    6. Alpha-S2-casein was less effective at preventing fibril formation by modified kappa-casein, whereas alpha- and alpha-S1 casein were comparably potent inhibitors. PMID: 21457703
    7. Single or multiple amino acid substitutions within IgE-binding epitopes result in reduced binding of milk-specific IgE antibodies. Critical amino acids should be evaluated with individual patient sera to determine B-cell-epitope heterogeneity. PMID: 12897753
    8. determination of T cell reactive epitopes PMID: 15482858
    9. EMSA analysis comparing allelic variants of a polymorphic AP-1 binding site in the promoter region of CSN1S1; specific and reduced protein binding of oligonucleotides containing the G variant of the CSN1S1-175bp binding site was shown PMID: 15905454
    10. An isoelectrofocusing pattern was identified, which may result from a novel CSN1S1 variant, named CSN1S1*I, migrating at an intermediate position between CSN1S1*B and CSN1S1*C. PMID: 18096958
    11. Substitution effects of paternal CSN2alpha (s1) allele versus CSN2 alpha(s2) allele on protein yield deviations (YDs) are significant, whereas their effects on milk and fat YDs are not. PMID: 18263971

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Alpha-casein family
  • 組織特異性：
    Mammary gland specific. Secreted in milk.
  • 數據庫鏈接：