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  4. Recombinant Bovine Fibromodulin (FMOD)

Recombinant Bovine Fibromodulin (FMOD)

  • 中文名稱：
    牛FMOD重組蛋白
  • 貨號：
    CSB-YP008755BO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛FMOD重組蛋白
  • 貨號：
    CSB-EP008755BO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛FMOD重組蛋白
  • 貨號：
    CSB-EP008755BO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛FMOD重組蛋白
  • 貨號：
    CSB-BP008755BO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛FMOD重組蛋白
  • 貨號：
    CSB-MP008755BO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    FMOD
  • Uniprot No.：
  • 別名：
    FMODFibromodulin; FM; Collagen-binding 59 kDa protein; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    19-376
  • 氨基酸序列
    QY EEDSHWWFQF LRNQQSTYDD PYDPYPYEPY EPYPYGGEEG PAYAYGSPPQ PEPRDCPQEC DCPPNFPTAM YCDNRNLKYL PFVPSRMKYV YFQNNQISSI QEGVFDNATG LLWIALHGNQ ITSDKVGKKV FSKLRHLERL YLDHNNLTRI PSPLPRSLRE LHLDHNQISR VPNNALEGLE NLTALYLHHN EIQEVGSSMK GLRSLILLDL SYNHLRKVPD GLPSALEQLY LEHNNVFSVP DSYFRGSPKL LYVRLSHNSL TNNGLASNTF NSSSLLELDL SYNQLQKIPP VSTNLENLYL QGNRINEFSI SSFCTVVDVM NFSKLQVLRL DGNEIKRSAM PADAPLCLRL ASLIEI
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
  • 基因功能參考文獻(xiàn)：
    1. Some nine tyrosine residues in the fibromodulin N-terminal domain are O-sulfated, a posttranslational modification often involved in protein interactions. Taken together, this study suggests a novel, regulatory function for tyrosine sulfation in Fibromodulin, which controls the interaction with collagen type I. PMID: 27634037
    2. There are discrete populations of fibromodulin within articular cartilage, which may have differing impacts upon tissue processes. PMID: 21892771
    3. MMP-13 treatment of fresh articular cartilage results in cleaved fibromodulin fragments PMID: 14660626
    4. fibromodulin and decorin have similarities and differences that may represent the biochemical basis of redundancy in small leucine-rich proteoglycan function PMID: 17522997
    5. tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of heparin-binding proteins, including bioactive factors PMID: 19700767

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  • 亞細(xì)胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Small leucine-rich proteoglycan (SLRP) family, SLRP class II subfamily
  • 數(shù)據(jù)庫鏈接：