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  4. Recombinant Bovine NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR)

Recombinant Bovine NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR)

  • 中文名稱：
    牛FDXR重組蛋白
  • 貨號(hào)：
    CSB-BP008575BO
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛FDXR重組蛋白
  • 貨號(hào)：
    CSB-EP008575BO-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛FDXR重組蛋白
  • 貨號(hào)：
    CSB-MP008575BO
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Name:FDXR Synonyms:ADXR
  • Uniprot No.：
  • 別名：
    FDXR; ADXRNADPH:adrenodoxin oxidoreductase; mitochondrial; AR; Adrenodoxin reductase; EC 1.18.1.6; Ferredoxin--NADP(+) reductase; Ferredoxin reductase
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    33-492
  • 氨基酸序列
    STQEQTPQ ICVVGSGPAG FYTAQHLLKH HSRAHVDIYE KQLVPFGLVR FGVAPDHPEV KNVINTFTQT ARSDRCAFYG NVEVGRDVTV QELQDAYHAV VLSYGAEDHQ ALDIPGEELP GVFSARAFVG WYNGLPENRE LAPDLSCDTA VILGQGNVAL DVARILLTPP DHLEKTDITE AALGALRQSR VKTVWIVGRR GPLQVAFTIK ELREMIQLPG TRPMLDPADF LGLQDRIKEA ARPRKRLMEL LLRTATEKPG VEEAARRASA SRAWGLRFFR SPQQVLPSPD GRRAAGIRLA VTRLEGIGEA TRAVPTGDVE DLPCGLVLSS IGYKSRPIDP SVPFDPKLGV VPNMEGRVVD VPGLYCSGWV KRGPTGVITT TMTDSFLTGQ ILLQDLKAGH LPSGPRPGSA FIKALLDSRG VWPVSFSDWE KLDAEEVSRG QASGKPREKL LDPQEMLRLL GH
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
  • 基因功能參考文獻(xiàn)：
    1. We constructed cDNA including genes of the bovine cholesterol hydroxylase/lyase (CHL) system proteins-cytochrome P450scc (CYP11A1), adrenodoxin (Adx) and adrenodoxin reductase (AdR), that are fused into a single ORF using FMDV 2A nucleotide sequences. PMID: 28799023
    2. S. pombe is either very robust to mitochondrial reactive oxygen species (ROS) production or does not undergo apoptotic cell death in response to mitochondrial ROS at all. PMID: 17885803
  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein.
  • 蛋白家族：
    Ferredoxin--NADP reductase type 1 family
  • 組織特異性：
    Detected in adrenal cortex and corpus luteum (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：