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  4. Recombinant Conus vexillum Alpha-conotoxin VxXXC

Recombinant Conus vexillum Alpha-conotoxin VxXXC

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  • 中文名稱：
    Recombinant Conus vexillum Alpha-conotoxin VxXXC
  • 貨號：
    CSB-EP314942DWK
  • 規(guī)格：
    ￥2328
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    Alpha-conotoxin VxXXC; VxXIIC
  • 種屬：
    Conus vexillum (Flag cone)
  • 蛋白長度：
    Full Length
  • 來源：
    E.coli
  • 分子量：
    25.3 kDa
  • 表達區(qū)域：
    1-47aa
  • 氨基酸序列
    DLRQCTRNAPGSTWGRCCLNPMCGNFCCPRSGCTCAYNWRRGIYCSC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Tris-based buffer,50% glycerol
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產(chǎn)品描述：

    The recombinant Conus vexillum alpha-conotoxin VxXXC is expressed in E.coli. Its expression region is the full-length amino acid sequence (1-47AA) of the Conus vexillum. It is fused with 10xHis-SUMO-tag at the N terminus and Myc-tag at the C-terminus. Its purity is greater than 85% determined by the SDS-PAGE. On the gel, this recombinant protein migrated to the molecular weight band of approximately 25 kDa. It is available now.

  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes. VxXXA and VxXXB inhibit alpha-7/CHRNA7 and alpha-3-beta-2/CHRNA3-CHRNB2 nAChR more efficiently than VxXXC. VxXXB is the most effective at inhibiting alpha-4-beta-2/CHRNA4-CHRNB2 nAChR, followed by VxXXC and VxXXA.
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Conotoxin D superfamily
  • 組織特異性：
    Expressed by the venom duct.