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  4. Recombinant Danio rerio Cytochrome P450 26B1 (cyp26b1), partial

Recombinant Danio rerio Cytochrome P450 26B1 (cyp26b1), partial

  • 中文名稱：
    Recombinant Danio rerio Cytochrome P450 26B1(cyp26b1) ,partial
  • 貨號：
    CSB-YP721935DIL
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Danio rerio Cytochrome P450 26B1(cyp26b1) ,partial
  • 貨號：
    CSB-EP721935DIL
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Danio rerio Cytochrome P450 26B1(cyp26b1) ,partial
  • 貨號：
    CSB-EP721935DIL-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Danio rerio Cytochrome P450 26B1(cyp26b1) ,partial
  • 貨號：
    CSB-BP721935DIL
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Danio rerio Cytochrome P450 26B1(cyp26b1) ,partial
  • 貨號：
    CSB-MP721935DIL
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    cyp26b1
  • Uniprot No.：
  • 別名：
    cyp26b1Cytochrome P450 26B1; Cyp26B1; EC 1.14.13.-; Retinoic acid-metabolizing cytochrome
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Appears to be involved in the inactivation of all-trans-retinoic acid (RA). Plays a role in skeletal development.
  • 基因功能參考文獻：
    1. we find that Cyp26 function is required in a short time window that overlaps the dynamic window of tenoblast condensation. However, cyp26b1 expression is largely restricted to regions between tenoblast condensations during this time PMID: 29227993
    2. The data demonstrate that RA-induced osteoblast-preosteocyte transitioning has multiple effects on developing bone in Cyp26b1 mutants, ranging from gain to loss of bone, depending on the allelic strength, the developmental stage and the cellular context. PMID: 26903503
    3. cyp26b1 is involved in limiting the activity of retinoic acid. Zygotic cyp26b1 was localized to presumptive rhombomere 3 and rhombomere 4 at early two-somite (2S) stage. Expression expands anteriorly to include rhombomere 2 at the 10S stage. PMID: 15661642
    4. effects of the inhibitor rather than excess retinoic acid most closely phenocopied the jaw defects seen with the Cyp26B1 morpholino PMID: 17616924
    5. Cyp26b1 is expressed within osteoblast cells, demonstrating that retinoic acid levels within these cells need to be tightly controlled PMID: 18927155
    6. cyp26b1 mutants may serve as a model to study the etiology of human vertebral disorders such as Klippel-Feil anomaly PMID: 18927157

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  • 亞細胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
  • 蛋白家族：
    Cytochrome P450 family
  • 數(shù)據(jù)庫鏈接：