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  4. Recombinant Drosophila melanogaster Tyrosine-protein kinase Src64B (Src64B), partial

Recombinant Drosophila melanogaster Tyrosine-protein kinase Src64B (Src64B), partial

  • 中文名稱：
    黑腹果蠅Src64B重組蛋白
  • 貨號：
    CSB-YP360550DLU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅Src64B重組蛋白
  • 貨號：
    CSB-EP360550DLU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅Src64B重組蛋白
  • 貨號：
    CSB-EP360550DLU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅Src64B重組蛋白
  • 貨號：
    CSB-BP360550DLU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅Src64B重組蛋白
  • 貨號：
    CSB-MP360550DLU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Src64B
  • Uniprot No.：
  • 別名：
    Src64B; Src1; CG7524; Tyrosine-protein kinase Src64B; Dsrc64; EC 2.7.10.2
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    May play a role in the development of neural tissue and smooth muscle.
  • 基因功能參考文獻：
    1. Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo PMID: 26628094
    2. a novel essential role for Src in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo. PMID: 24788409
    3. Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified. PMID: 22132220
    4. Maternal src64 regulates microfilament contraction throughout cellularization, but that zygotic src64 makes a small, but normally nonessential, contribution during late cellularization. PMID: 21735539
    5. Src64B overexpression induced the formation of specialized haemocytes (lamellocytes), but had no effect on circulating plasmatocyte concentration. Src64B overexpression induced F-actin formation and Jun kinase activation in plasmatocytes. PMID: 20375590
    6. Src64 acts in a cell-autonomous fashion and is likely to interact with the previously-identified linotte/derailed receptor tyrosine kinase in mushroom body development PMID: 14608664
    7. Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis. PMID: 15979065
    8. Study shows that in Drosophila epithelia in situ, levels of Src signaling determine the cellular outcome of Src activation; apoptotic cell death was triggered at high Src levels; lower levels directed antiapoptotic signals while promoting proliferation. PMID: 17974969
    9. Src64B is required for tracheal development and to increase the rate of adherens junction turnover. PMID: 18305002

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  • 蛋白家族：
    Protein kinase superfamily, Tyr protein kinase family, SRC subfamily
  • 組織特異性：
    After the first 8 hours of development, accumulates almost exclusively in neural tissues such as the brain, ventral nerve chord, and eye-antennal disks, and in differentiating smooth muscle.
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG7524

    STRING: 7227.FBpp0293527

    UniGene: Dm.1531