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  4. Recombinant Human Autophagy-related protein 9B (ATG9B), partial

Recombinant Human Autophagy-related protein 9B (ATG9B), partial

  • 中文名稱：
    Recombinant Human Autophagy-related protein 9B(ATG9B) ,partial
  • 貨號：
    CSB-YP721119HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Autophagy-related protein 9B(ATG9B) ,partial
  • 貨號：
    CSB-EP721119HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Autophagy-related protein 9B(ATG9B) ,partial
  • 貨號：
    CSB-EP721119HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Autophagy-related protein 9B(ATG9B) ,partial
  • 貨號：
    CSB-BP721119HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Autophagy-related protein 9B(ATG9B) ,partial
  • 貨號：
    CSB-MP721119HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    APG9 like 2; APG9-like 2; Apg912; APG9L2; Apgdc2; ATG9 autophagy related 9 homolog B (S. cerevisiae); Atg9b; ATG9B_HUMAN; Autophagy 9 like 2 protein; Autophagy related protein 9B; Autophagy-related protein 9B; Endothelial nitric oxide synthase antisense; eONE; Gm574; Nitric oxide synthase 3 antisense; Nitric oxide synthase 3 overlapping antisense gene protein; Nitric oxide synthase 3-overlapping antisense gene protein; NOS3AS; Protein sONE; SONE
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

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靶點詳情

  • 功能：
    Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion. In addition to autophagy, also plays a role in necrotic cell death.
  • 基因功能參考文獻(xiàn)：
    1. there is a close relationship between CRP and ATG9B in clear cell renal cell carcinomacarcinogenesis. PMID: 28923830
    2. This study highlights the transcriptional inactivation mechanisms of ATG2B, ATG4D, ATG9A and ATG9B promoter methylation status and the possible origin of autophagy signal pathway repression in invasive ductal carcinomas. PMID: 27265029
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    4. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 19423540
    6. Observational study of gene-disease association. (HuGE Navigator) PMID: 20406964
    7. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20416077
    8. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20438785
    9. The role of Atg9 trafficking in yeast and mammalian autophagy, is summarised. PMID: 20083107
    10. Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and genetic testing. (HuGE Navigator) PMID: 19948975
    11. APG9L2 is highly expressed in placenta (trophoblast cells) and pituitary gland of adult tissues. PMID: 15755735
    12. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 19423521
    13. Observational study of gene-disease association. (HuGE Navigator) PMID: 19197948

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  • 亞細(xì)胞定位：
    Preautophagosomal structure membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ATG9 family
  • 組織特異性：
    Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 21899

    OMIM: 612205

    KEGG: hsa:285973

    UniGene: Hs.707300