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  4. Recombinant Human DDB1- and CUL4-associated factor 16 (DCAF16)

Recombinant Human DDB1- and CUL4-associated factor 16 (DCAF16)

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  • 中文名稱：
    Recombinant Human DDB1- and CUL4-associated factor 16(DCAF16)
  • 貨號：
    CSB-EP865168HU
  • 規(guī)格：
    ￥1836
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP865168HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DCAF16.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP865168HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DCAF16.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    DCAF16
  • Uniprot No.：
  • 別名：
    DCAF16; C4orf30DDB1- and CUL4-associated factor 16
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length
  • 來源：
    E.coli
  • 分子量：
    31.2 kDa
  • 表達區(qū)域：
    1-216aa
  • 氨基酸序列
    MGPRNPSPDHLSESESEEEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Tris-based buffer，50% glycerol
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產(chǎn)品描述：
    Recombinant Human DDB1- and CUL4-associated factor 16(DCAF16) is a full length protein expressed with N-terminal 10xHis-tagged and C-terminal Myc-tagged in the E.coli. Its expression region corresponds to 1-216aa of human DCAF16 protein. Its purity was determined by SDS-PAGE and reached up to 85%. Under reducing conditions, a molecular weight band of around 35 kDa was visualized on the gel. Furthermore, this protein underwent validation via the LC-MS/MS analysis. This recombinant DCAF16 protein may be used to synthesize antibodies against DCAF16 or on the studies of DCAF16-associated signal transduction.
    DCAF16 is a gene on chromosome 4p15.31 that encodes a protein thought to function as a substrate recognition component for CUL4-DDB1 E3 ubiquitin-protein ligase complex, which mediates ubiquitination and proteasome-dependent degradation of nuclear proteins. This protein is involved in the pathway protein ubiquitination, which is part of protein modification.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Functions as a substrate recognition component for CUL4-DDB1 E3 ubiquitin-protein ligase complex, which mediates ubiquitination and proteasome-dependent degradation of nuclear proteins.
  • 亞細胞定位：
    Nucleus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25987

    KEGG: hsa:54876

    STRING: 9606.ENSP00000371682

    UniGene: Hs.614787