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  4. Recombinant Human EGF-like module-containing mucin-like hormone receptor-like 3 (EMR3), partial

Recombinant Human EGF-like module-containing mucin-like hormone receptor-like 3 (EMR3), partial

  • 中文名稱：
    Recombinant Human EGF-like module-containing mucin-like hormone receptor-like 3(EMR3),partial
  • 貨號：
    CSB-YP861168HU1
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human EGF-like module-containing mucin-like hormone receptor-like 3(EMR3),partial
  • 貨號：
    CSB-EP861168HU1
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human EGF-like module-containing mucin-like hormone receptor-like 3(EMR3),partial
  • 貨號：
    CSB-EP861168HU1-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human EGF-like module-containing mucin-like hormone receptor-like 3(EMR3),partial
  • 貨號：
    CSB-BP861168HU1
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human EGF-like module-containing mucin-like hormone receptor-like 3(EMR3),partial
  • 貨號：
    CSB-MP861168HU1
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    ADGRE3; EMR3; UNQ683/PRO1562; Adhesion G protein-coupled receptor E3; EGF-like module receptor 3; EGF-like module-containing mucin-like hormone receptor-like 3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes-derived macrophages and activated neutrophils.
  • 基因功能參考文獻(xiàn)：
    1. Given the poor survival associated with high levels of EMR-3 expression in glioma patients, impetus is provided to explore EMR-3 as a potential therapeutic target. PMID: 20827226
    2. Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included increased EMR1&3. PMID: 20625511
    3. The expression of EGF-TM7 receptors on myeloid cells is differentially regulated. EMR3 is the first family member found mainly on granulocytes. PMID: 17108056
  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.; [Isoform 3]: Secreted.
  • 蛋白家族：
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 組織特異性：
    Displays a predominantly leukocyte-restricted expression, with highest levels in neutrophils, monocytes and macrophages.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 23647

    OMIM: 606101

    KEGG: hsa:84658

    STRING: 9606.ENSP00000253673

    UniGene: Hs.658712