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  4. Recombinant Human Heat shock 70 kDa protein 13 (HSPA13)

Recombinant Human Heat shock 70 kDa protein 13 (HSPA13)

  • 中文名稱：
    人HSPA13重組蛋白
  • 貨號：
    CSB-RP109644h
  • 規(guī)格：
    ￥1344
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    HSPA13
  • Uniprot No.：
  • 別名：
    Heat shock 70 kDa protein 13; HEAT SHOCK 70-KD PROTEIN 13; heat shock protein 70kDa family, member 13; heat shock protein70kDa family, member13; HSP13_HUMAN; HSPA13; MGC133835; Microsomal stress 70 protein ATPase core; Microsomal stress-70 protein ATPase core; STCH; Stress 70 protein chaperone microsome associated 60 kDa protein; Stress-70 protein chaperone microsome-associated 60 kDa protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 來源：
    E.coli
  • 分子量：
    76.6kDa
  • 表達區(qū)域：
    23-471aa
  • 氨基酸序列
    QQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal GST-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Has peptide-independent ATPase activity.
  • 基因功能參考文獻：
    1. novel role of STCH in the regulation of pHi through site-specific interactions with NBCe1-B and NHE1 and subsequent modulation of membrane transporter expression. PMID: 23303189
    2. in the Japanese population, STCH might be a new candidate for conferring susceptibility to gastric cancer PMID: 16087163
    3. These results suggest that STCH has a role in cell survival via modulation of the TRAIL-mediated cell death pathway. PMID: 18793616
    4. An entirely novel path is revealed toward therapeutic intervention of tauopathies by inhibition of the previously untargeted ATPase activity of Hsp70. PMID: 19793966
  • 亞細胞定位：
    Microsome. Endoplasmic reticulum.
  • 蛋白家族：
    Heat shock protein 70 family
  • 組織特異性：
    Constitutively expressed in all tissues.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11375

    OMIM: 601100

    KEGG: hsa:6782

    STRING: 9606.ENSP00000285667

    UniGene: Hs.352341