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  4. Recombinant Human Hydrocephalus-inducing protein homolog (HYDIN), partial

Recombinant Human Hydrocephalus-inducing protein homolog (HYDIN), partial

  • 中文名稱：
    人HYDIN重組蛋白
  • 貨號：
    CSB-YP670104HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人HYDIN重組蛋白
  • 貨號：
    CSB-EP670104HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人HYDIN重組蛋白
  • 貨號：
    CSB-EP670104HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人HYDIN重組蛋白
  • 貨號：
    CSB-BP670104HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人HYDIN重組蛋白
  • 貨號：
    CSB-MP670104HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    HYDIN
  • Uniprot No.：
  • 別名：
    CILD5; Hydin; HYDIN axonemal central pair apparatus protein; HYDIN_HUMAN; HYDIN1; HYDIN2; Hydrocephalus-inducing protein homolog; PPP1R31; Protein phosphatase 1 regulatory subunit 31
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Required for ciliary motility.
  • 基因功能參考文獻：
    1. Three loci with high mutation frequencies, the 138665410 FOXL2 gene variant, the 23862952 MYH6 gene variant, and the 71098693 HYDIN gene variant were found to be significantly associated with sporadic Atrial Septal Defect (P<0.05); variants in FOXL2 and MYH6 were found in patients with isolated, sporadic Atrial Septal Defect (P<5x10-4). PMID: 29505555
    2. The results suggest frequent and coordinated adaptive immune responses against HYDIN variants in patients with cancer. PMID: 24777681
    3. We have found that the human HYDIN locus has been very recently duplicated, with a nearly identical 360-kb paralogous segment inserted on chromosome 1q21.1 PMID: 16938426
  • 相關(guān)疾?。?/div>
    Ciliary dyskinesia, primary, 5 (CILD5)
  • 亞細胞定位：
    Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19368

    OMIM: 608647

    KEGG: hsa:54768

    STRING: 9606.ENSP00000314736

    UniGene: Hs.351914