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  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Kyphoscoliosis peptidase (KY)

Recombinant Human Kyphoscoliosis peptidase (KY)

  • 中文名稱(chēng)：
    人KY重組蛋白
  • 貨號(hào)：
    CSB-YP012702HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    人KY重組蛋白
  • 貨號(hào)：
    CSB-EP012702HU
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    人KY重組蛋白
  • 貨號(hào)：
    CSB-EP012702HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    人KY重組蛋白
  • 貨號(hào)：
    CSB-BP012702HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    人KY重組蛋白
  • 貨號(hào)：
    CSB-MP012702HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    KY
  • Uniprot No.：
  • 別名：
    KY; KY_HUMAN; Kyphoscoliosis peptidase
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-561
  • 氨基酸序列
    MELKKDINAV SIDMLLIVHS EKRRAAQGTL SDQQANPSSL LQRGGGFQGV GNGVRRWQKL EGNDFHENLV EKQHPQQPQV ITSYNSQGTQ LTVEVHPRDA MPQLLKKFSL AKRLQGDKNG NTRPRQPGGK DAHAYPWDRS SLKSMSLDLQ QFEKLDIYAS QVTAKSGLDE LVSDLLQEAH TDLERVRAIW IWICHHIEYD IAAAQEKDRQ AFKPTDILRT QKTNCDGYAG LFERMCRLAG VQCMTVPGYS KGFGYQTGQS FSGEFDHAWN AVYLEGRWHL VDSTWGSGLV DTITSKFTFL YNEFYFLTHP ALFIEDHFPD NKNWQLLKPP QSLRQFENNM YHKSEFYNKG MLSAHPETSM IRTVNGKATV TIESCAPTLF MFMLNGKQEH GLLSLRKNGM KLEVYPPTMG THKLQIFAKG NSDIYSSVLE YTLKCNYVDM GVQLPAELHQ PVGPSWFSEQ MGIMKPSHPD PIIHTSDGRC SISFSVEEGI NVLASLHGDD GPITEETQRR YIFQLHREKQ TELKVQLPHA GKFALKIYVM VLENANHNFY SYILKYKVNA Q
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC.
  • 基因功能參考文獻(xiàn)：
    1. This study shown Kyphoscoliosis peptidase (KY) mutation causes a novel congenital myopathy with core targetoid defects in two bother. PMID: 27484770
    2. Homozygous KY mutation was identified as a cause of progressive hereditary spastic paraplegia. High KY transcript levels were demonstrated in muscular organs and lower expression in the CNS. PMID: 28488683
    3. Homozygous c.1071delG, p.(Thr358Leufs*3) variant of KY causes neuromuscular disorder by introducing a premature stop codon. PMID: 27485408
    4. KY expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
    5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614

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  • 相關(guān)疾?。?/div>
    Myopathy, myofibrillar, 7 (MFM7)
  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line.
  • 蛋白家族：
    Transglutaminase-like superfamily
  • 組織特異性：
    Highly expressed in skeletal muscle.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 26576

    OMIM: 605739

    KEGG: hsa:339855

    STRING: 9606.ENSP00000397598

    UniGene: Hs.146730