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  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Lipoyltransferase 1, mitochondrial (LIPT1)

Recombinant Human Lipoyltransferase 1, mitochondrial (LIPT1)

  • 中文名稱：
    人LIPT1重組蛋白
  • 貨號(hào)：
    CSB-YP896479HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    人LIPT1重組蛋白
  • 貨號(hào)：
    CSB-EP896479HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人LIPT1重組蛋白
  • 貨號(hào)：
    CSB-BP896479HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人LIPT1重組蛋白
  • 貨號(hào)：
    CSB-MP896479HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    LIPT1
  • Uniprot No.：
  • 別名：
    Lipoate biosynthesis protein; Lipoate-protein ligase; Lipoyl ligase; Lipoyltransferase 1; Lipoyltransferase 1 mitochondrial; LIPT_HUMAN; Lipt1; mitochondrial
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    26-373
  • 氨基酸序列
    KTVKN GLILQSISND VYQNLAVEDW IHDHMNLEGK PILFFWQNSP SVVIGRHQNP WQECNLNLMR EEGIKLARRR SGGGTVYHDM GNINLTFFTT KKKYDRMENL KLIVRALNAV QPQLDVQATK RFDLLLDGQF KISGTASKIG RTTAYHHCTL LCSTDGTFLS SLLKSPYQGI RSNATASIPS LVKNLLEKDP TLTCEVLMNA VATEYAAYHQ IDNHIHLINP TDETLFPGIN SKAKELQTWE WIYGKTPKFS INTSFHVLYE QSHLEIKVFI DIKNGRIEIC NIEAPDHWLP LEIRDKLNSS LIGSKFCPTE TTMLTNILLR TCPQDHKLNS KWNILCEKIK GIM
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
  • 基因功能參考文獻(xiàn)：
    1. LIPT1 protein is required for lipoylation and activation of 2-ketoacid dehydrogenases in humans. PMID: 24256811
    2. Data report a putative case of impaired free or H protein-derived lipoic acid attachment due to LIPT1 mutations as a cause of PDH and alpha-KGDH deficiencies. PMID: 24341803
  • 相關(guān)疾?。?/div>
    Lipoyltransferase 1 deficiency (LIPT1D)
  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    LplA family
  • 組織特異性：
    Highly expressed in skeletal muscle and heart, moderately in kidney and pancreas, and detected at lower levels in liver, brain, placenta and lung.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 29569

    OMIM: 610284

    KEGG: hsa:51601

    STRING: 9606.ENSP00000342071

    UniGene: Hs.719172