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  4. Recombinant Human N-acetylneuraminate 9-O-acetyltransferase (CASD1), partial

Recombinant Human N-acetylneuraminate 9-O-acetyltransferase (CASD1), partial

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  • 中文名稱：
    Recombinant Human N-acetylneuraminate 9-O-acetyltransferase(CASD1),partial
  • 貨號：
    CSB-EP846683HU
  • 規(guī)格：
    ￥1344
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    CASD1
  • Uniprot No.：
  • 別名：
    CASD1; C7orf12; Nbla04196N-acetylneuraminate 9-O-acetyltransferase; EC 2.3.1.45; CAS1 domain-containing protein 1; Sialate O-acetyltransferase; SOAT
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 來源：
    E.coli
  • 分子量：
    47.2kDa
  • 表達區(qū)域：
    39-313aa
  • 氨基酸序列
    ASRRYRGNDSCEYLLSSGRFLGEKVWQPHSCMMHKYKISEAKNCLVDKHIAFIGDSRIRQLFYSFVKIINPQFKEEGNKHENIPFEDKTASVKVDFLWHPEVNGSMKQCIKVWTEDSIAKPHVIVAGAATWSIKIHNGSSEALSQYKMNITSIAPLLEKLAKTSDVYWVLQDPVYEDLLSENRKMITNEKIDAYNEAAVSILNSSTRNSKSNVKMFSVSKLIAQETIMESLDGLHLPESSRETTAMILMNVYCNKILKPVDGSCCQPRPPVTLIQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    N-terminal 6xHis-SUMO-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    O-acetyltransferase that catalyzes 9-O-acetylation of sialic acids. Sialic acids are sugars at the reducing end of glycoproteins and glycolipids, and are involved in various processes such as cell-cell interactions, host-pathogen recognition.
  • 基因功能參考文獻：
    1. CASD1 is a sialate O-acetyltransferase and serves as key enzyme in the biosynthesis of 9-O-acetylated sialoglycans. PMID: 26169044
    2. human Cas1 protein is directly involved in O-acetylation of alpha2-8-linked sialic acids PMID: 20947662
  • 亞細胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    PC-esterase family, CASD1 subfamily
  • 組織特異性：
    Highly expressed in peripheral B lymphocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16014

    OMIM: 611686

    KEGG: hsa:64921

    STRING: 9606.ENSP00000297273

    UniGene: Hs.260041