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  4. Recombinant Human Neudesin (NENF)

Recombinant Human Neudesin (NENF)

  • 中文名稱：
    人NENF重組蛋白
  • 貨號(hào)：
    CSB-YP892354HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人NENF重組蛋白
  • 貨號(hào)：
    CSB-EP892354HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人NENF重組蛋白
  • 貨號(hào)：
    CSB-EP892354HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人NENF重組蛋白
  • 貨號(hào)：
    CSB-BP892354HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人NENF重組蛋白
  • 貨號(hào)：
    CSB-MP892354HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    NENF
  • Uniprot No.：
  • 別名：
    Cell growth inhibiting protein 47; Cell immortalization-related protein 2; CIR2; Nenf; NENF_HUMAN; Neudesin; Neuron derived neurotrophic factor; Neuron-derived neurotrophic factor; SCIRP10; SCIRP10 related protein; Secreted protein of unknown function; Spinal cord injury related protein 10; SPUF; SPUF protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    32-172
  • 氨基酸序列
    GQTPRPAER GPPVRLFTEE ELARYGGEEE DQPIYLAVKG VVFDVTSGKE FYGRGAPYNA LTGKDSTRGV AKMSLDPADL THDTTGLTAK ELEALDEVFT KVYKAKYPIV GYTARRILNE DGSPNLDFKP EDQPHFDIKD EF
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance.
  • 基因功能參考文獻(xiàn)：
    1. High NENF expression is associated with liver cancer. PMID: 24763612
    2. Human neudesin of 172 amino acids with high similarity ( approximately 91% identity) to mouse neudesin was identified; the human neudesin gene was mapped to chromosome 1p33. PMID: 15605373
    3. Describes the predicted heme-binding domains in the human neudesin protein sequence. PMID: 18056703
  • 亞細(xì)胞定位：
    Secreted, extracellular space. Mitochondrion. Endoplasmic reticulum.
  • 蛋白家族：
    Cytochrome b5 family, MAPR subfamily
  • 組織特異性：
    Ubiquitously expressed with high expression in heart. Over-expressed in various tumors including carcinomas of the uterine cervix, lymphoma, colon, lung, skin and leukemia, as well as carcinoma of the breast.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30384

    OMIM: 611874

    KEGG: hsa:29937

    STRING: 9606.ENSP00000355955

    UniGene: Hs.461787