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  4. Recombinant Human Probable crossover junction endonuclease EME2 (EME2)

Recombinant Human Probable crossover junction endonuclease EME2 (EME2)

  • 中文名稱：
    人EME2重組蛋白
  • 貨號：
    CSB-YP007635HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人EME2重組蛋白
  • 貨號：
    CSB-EP007635HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人EME2重組蛋白
  • 貨號：
    CSB-EP007635HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人EME2重組蛋白
  • 貨號：
    CSB-BP007635HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人EME2重組蛋白
  • 貨號：
    CSB-MP007635HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    EME2
  • Uniprot No.：
  • 別名：
    EME1; S. pombe; homolog of; 2; Eme2; EME2_HUMAN; essential meiotic endonuclease 1 homolog 2; essential meiotic endonuclease 1; S.pombe; homolog of; 2; essential meiotic structure-specific endonuclease subunit 2; gs125; homolog of yeast EME1 endonuclease 2; Probable crossover junction endonuclease EME2; SLX2 structure-specific endonuclease subunit homolog B; SLX2B
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full length protein
  • 表達(dá)區(qū)域：
    1-379
  • 氨基酸序列
    MARVGPGRAG VSCQGRGRGR GGSGQRRPPT WEISDSDAED SAGSEAAARA RDPAGERRAA AEALRLLRPE QVLKRLAVCV DTAILEDAGA DVLMEALEAL GCECRIEPQR PARSLRWTRA SPDPCPRSLP PEVWAAGEQE LLLLLEPEEF LQGVATLTQI SGPTHWVPWI SPETTARPHL AVIGLDAYLW SRQHVSRGTQ QPESPKVAGA EVAVSWPEVE EVRACLSWAL VLLQLWANLD VLLVASWQEL SRHVCAVTKA LAQYPLKGGR ITSRQYRESQ AFSFCTAGRW AAGEPVARDG AGLQAAWRRQ IRQFSRVSPA VADAVVTAFP SPRLLQQALE ACSTERERMG LLAVGPDLSR RICLFLTTAN PDLLLDLGS
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures.
  • 基因功能參考文獻(xiàn)：
    1. The results indicate that MUS81-EME2 is a more active endonuclease than MUS81-EME1 and exhibits broader substrate specificity. PMID: 24371268
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    EME1/MMS4 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 27289

    OMIM: 610886

    KEGG: hsa:197342

    UniGene: Hs.7247