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  4. Recombinant Human Protein BTG4 (BTG4)

Recombinant Human Protein BTG4 (BTG4)

  • 中文名稱：
    Recombinant Human Protein BTG4(BTG4)
  • 貨號：
    CSB-YP878918HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Protein BTG4(BTG4)
  • 貨號：
    CSB-EP878918HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Protein BTG4(BTG4)
  • 貨號：
    CSB-EP878918HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Protein BTG4(BTG4)
  • 貨號：
    CSB-BP878918HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Protein BTG4(BTG4)
  • 貨號：
    CSB-MP878918HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    BTG4
  • Uniprot No.：
  • 別名：
    B cell translocation gene 4; BTG family member 4; Btg4; BTG4_HUMAN; MGC33003; PC3B ; Protein BTG4; Protein PC3b
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-223
  • 氨基酸序列
    MRDEIATTVF FVTRLVKKHD KLSKQQIEDF AEKLMTILFE TYRSHWHSDC PSKGQAFRCI RINNNQNKDP ILERACVESN VDFSHLGLPK EMTIWVDPFE VCCRYGEKNH PFTVASFKGR WEEWELYQQI SYAVSRASSD VSSGTSCDEE SCSKEPRVIP KVSNPKSIYQ VENLKQPFQS WLQIPRKKNV VDGRVGLLGN TYHGSQKHPK CYRPAMHRLD RIL
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Adapter protein that bridges CNOT7, a catalytic subunit of the CCR4-NOT complex, to EIF4E. Facilitates maternal mRNAs decay during the maturation of oocytes and in the fertilized egg, and is required for the maternal-zygotic transition (MZT), zygotic cleavage and initiation of embryonic development.
  • 基因功能參考文獻：
    1. BTG4 could contribute to chronic lymphocytic leykemia pathogenesis following inactivation by haploinsufficiency. PMID: 15672409
    2. miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC PMID: 18519671
    3. these data support BTG4 as a candidate tumor suppressor gene that is epigenetically silenced in the majority of gastric cancers. PMID: 19576178
  • 蛋白家族：
    BTG family
  • 組織特異性：
    Expressed in oocytes after germinal vesicle breakdown. Expressed in testis and in olfactory epithelium.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13862

    OMIM: 605673

    KEGG: hsa:54766

    STRING: 9606.ENSP00000348300

    UniGene: Hs.128180