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  4. Recombinant Human Protein FAM3A (FAM3A)

Recombinant Human Protein FAM3A (FAM3A)

  • 中文名稱：
    人FAM3A重組蛋白
  • 貨號：
    CSB-YP008226HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人FAM3A重組蛋白
  • 貨號：
    CSB-EP008226HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人FAM3A重組蛋白
  • 貨號：
    CSB-EP008226HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人FAM3A重組蛋白
  • 貨號：
    CSB-BP008226HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人FAM3A重組蛋白
  • 貨號：
    CSB-MP008226HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    FAM3A
  • Uniprot No.：
  • 別名：
    2-19; 2.19; Cytokine-like protein 2-19; DLD; DXS560S; FAM3A; FAM3A_HUMAN; family with sequence similarity 3; member A; Protein FAM3A; XAP 7
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    34-230
  • 氨基酸序列
    FPRIQQL FTSPESSVTA APRARKYKCG LPQPCPEEHL AFRVVSGAAN VIGPKICLED KMLMSSVKDN VGRGLNIALV NGVSGELIEA RAFDMWAGDV NDLLKFIRPL HEGTLVFVAS YDDPATKMNE ETRKLFSELG SRNAKELAFR DSWVFVGAKG VQNKSPFEQH VKNSKHSNKY EGWPEALEME GCIPRRSTAS
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    May act as a defensin against invading fungal microorganisms.
  • 基因功能參考文獻：
    1. These results suggest that C/EBPbeta plays an important role in regulating FAM3A promoter activity and FAM3A inhibits adipocyte differentiation. PMID: 27688071
    2. In the present study, we report a putative human homologue of the antimicrobial Drosophila-derived drosomycin, designated drosomycin-like defensin (DLD), with specific antifungal activity. PMID: 18212107
    3. FAM3A plays crucial roles in the regulation of glucose and lipid metabolism in the liver, where it activates the PI3K-Akt signaling pathway by way of a Ca(2+) /CaM-dependent mechanism PMID: 24806753
    4. Upregulation of FAM3A by PPARgamma activation is correlated with increased pAkt level in liver cells PMID: 23562554
    5. Expressed prominently in the vascular endothelium, particularly capillaries, also in islets of Langerhans. PMID: 12160727

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    FAM3 family
  • 組織特異性：
    In similar amounts in testis, pancreas, adrenal, placenta, brain, fetal brain, liver, kidney, skeletal muscle and heart.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13749

    OMIM: 300492

    KEGG: hsa:60343

    STRING: 9606.ENSP00000352955

    UniGene: Hs.289108