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  4. Recombinant Human Zinc finger C4H2 domain-containing protein (ZC4H2)

Recombinant Human Zinc finger C4H2 domain-containing protein (ZC4H2)

  • 中文名稱：
    人ZC4H2重組蛋白
  • 貨號：
    CSB-YP873628HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人ZC4H2重組蛋白
  • 貨號：
    CSB-EP873628HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人ZC4H2重組蛋白
  • 貨號：
    CSB-EP873628HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人ZC4H2重組蛋白
  • 貨號：
    CSB-BP873628HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人ZC4H2重組蛋白
  • 貨號：
    CSB-MP873628HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ZC4H2
  • Uniprot No.：
  • 別名：
    HCA127; Hepatocellular carcinoma-associated antigen 127; KIAA1166; OTTHUMP00000023432; Zc4h2; ZC4H2_HUMAN; Zinc finger C4H2 domain containing; Zinc finger C4H2 domain-containing protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-224
  • 氨基酸序列
    MADEQEIMCK LESIKEIRNK TLQMEKIKAR LKAEFEALES EERHLKEYKQ EMDLLLQEKM AHVEELRLIH ADINVMENTI KQSENDLNKL LESTRRLHDE YKPLKEHVDA LRMTLGLQRL PDLCEEEEKL SLDYFEKQKA EWQTEPQEPP IPESLAAAAA AAQQLQVARK QDTRQTATFR QQPPPMKACL SCHQQIHRNA PICPLCKAKS RSRNPKKPKR KQDE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation.
  • 基因功能參考文獻：
    1. The present patient confirms that female carriers can also be severely affected. Systematic clinical investigations of both males and females are needed to define the variety in nature and severity of phenotypes related to ZC4H2 variants. PMID: 28345801
    2. ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons PMID: 26056227
    3. ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity. PMID: 23623388
  • 相關(guān)疾?。?/div>
    Wieacker-Wolf syndrome (WRWF)
  • 亞細胞定位：
    Cytoplasm. Nucleus. Cell junction, synapse, postsynaptic cell membrane. Note=Upon transfection into mouse primary hippocampal neurons, localizes at excitatory, but not inhibitory, postsynaptic sites.
  • 組織特異性：
    Expressed in fetal tissues, including in brain, intestine, lung, kidney and muscle. Isoform 1 is expressed in numerous fetal brain regions. Isoform 3 is highly expressed in numerous fetal brain regions and spinal cord.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24931

    OMIM: 300897

    KEGG: hsa:55906

    STRING: 9606.ENSP00000363972

    UniGene: Hs.28249