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  4. Recombinant Human p53 and DNA damage-regulated protein 1 (PDRG1)

Recombinant Human p53 and DNA damage-regulated protein 1 (PDRG1)

  • 中文名稱：
    人PDRG1重組蛋白
  • 貨號：
    CSB-EP878890HU
  • 規(guī)格：
    ￥1344
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    PDRG1
  • Uniprot No.：
  • 別名：
    PDRG1; C20orf126; PDRGp53 and DNA damage-regulated protein 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length
  • 來源：
    E.coli
  • 分子量：
    31.5kDa
  • 表達區(qū)域：
    1-133aa
  • 氨基酸序列
    MLSPEAERVLRYLVEVEELAEEVLADKRQIVDLDTKRNQNREGLRALQKDLSLSEDVMVCFGNMFIKMPHPETKEMIEKDQDHLDKEIEKLRKQLKVKVNRLFEAQGKPELKGFNLNPLNQDELKALKVILKG
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal 6xHis-SUMO-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    May play a role in chaperone-mediated protein folding.
  • 基因功能參考文獻：
    1. It was found that PDRG1 could promote radio-resistance that involved the ATM-p53 signaling pathway in lung cancer cells. PMID: 27610824
    2. PDRG1 was significantly increased in tumors low of miR-214. PMID: 25706919
    3. PDRG1 expression is increased in multiple human malignancies suggesting it to be a high-value novel tumor marker that could play a role in cancer development and/or progression. PMID: 21193842
    4. Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation PMID: 14562055
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Prefoldin subunit beta family
  • 組織特異性：
    Predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16119

    OMIM: 610789

    KEGG: hsa:81572

    STRING: 9606.ENSP00000202017

    UniGene: Hs.435755