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  4. Recombinant Mouse Alpha-defensin 1 (Defa1)

Recombinant Mouse Alpha-defensin 1 (Defa1)

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  • 中文名稱：
    Recombinant Mouse Alpha-defensin 1(Defa1)
  • 貨號：
    CSB-EP006652MO
  • 規(guī)格：
    ￥2328
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    Defa1
  • Uniprot No.：
  • 別名：
    Defa1; Defcr; Defcr1Alpha-defensin 1; Cryptdin-1; Defensin-related cryptdin peptide
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 來源：
    E.coli
  • 分子量：
    34.1 kDa
  • 表達區(qū)域：
    59-93aa
  • 氨基酸序列
    LRDLVCYCRSRGCKGRERMNGTCRKGHLLYTLCCR
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal 6xHis-GST-tagged
  • 產品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Tris-based buffer,50% glycerol
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium.
  • 基因功能參考文獻：
    1. Mouse adenovirus 2 infection was enhanced by enteric alpha-defensins. PMID: 28622386
    2. Decreased alpha-defensin is associated with intestinal inflammation in a model of inflammatory bowel disease. PMID: 20222124
    3. cryptdin-1 and cryptdin-4 exhibit circadian oscillation PMID: 16129697
    4. the Arg5-Glu13 salt bridge in alpha-defensin is conserved for defensin in vivo stability PMID: 16246847
    5. MMP-7 activates mouse paneth cell pro-alpha-defensins PMID: 16822871

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Alpha-defensin family
  • 組織特異性：
    Paneth cells of the small bowel.
  • 數據庫鏈接：

    KEGG: mmu:13216

    UniGene: Mm.425522