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  4. Recombinant Mouse BPI fold-containing family B member 1 (Bpifb1)

Recombinant Mouse BPI fold-containing family B member 1 (Bpifb1)

In Stock
  • 中文名稱：
    Recombinant Mouse BPI fold-containing family B member 1 (Bpifb1)
  • 貨號(hào)：
    CSB-EP720239MO
  • 規(guī)格：
    ￥1536
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性：
    Not Test
  • 基因名：
    Bpifb1
  • Uniprot No.：
  • 別名：
    Long palate, lung and nasal epithelium carcinoma-associated protein 1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 來(lái)源：
    E.coli
  • 分子量：
    57.2 kDa
  • 表達(dá)區(qū)域：
    22-474aa
  • 氨基酸序列
    NVYPPAVLNLGPEVIQKHLTQALKDHDATAILQELPLLRAMQDKSGSIPILDSFVHTVLRYIIWMKVTSANILQLDVQPSTYDQELVVRIPLDMVAGLNTPLIKTIVEFQMSTEVQALIRVERSKSGPAHLNLSDCSSNESTLRLSLLHKLSFVVNSLAKNVMNLLVPALPQIVKNHLCPVIQQAFDDMYEDFLRLTTAPIALSPGALEFGLLSPAIQDSNILLNLKAKLLDSQARVTNWFNNSATSLMETTPDRAPFSLTVRQDLVNAIVTTLVPKEELVILLRFVIPDVARQLQMDIKEINAEAANKLGPTQMLKIFTHSTPHIVLNEGSARAAQSVVLEVFPTNTDVRPFFSLGIEASYEAQFFTEDNRLMLNFNNVSIERIKLMISDIKLFDPEVLKDTLTKILEYTLLPNENGKLRTGVPMSMSKALGYEKAMWSVSKGALKLTPASS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS. May be involved in formation of the left-right axis in the node of the developing embryo.
  • 基因功能參考文獻(xiàn)：
    1. BPIFB1 is a novel regulator of MUC5B expression in airway mucosa. PMID: 28851744
    2. Bpifb1 mRNA is upregulated in parotid acinar cells in NOD mice, but its expression is not related to the onset of diabetes. These findings suggest that high expression levels of Bpifb1 might predict disease traits before the onset of autoimmunity. PMID: 26769076
    3. Autoimmunity targeting the lung-specific antigen BPIFB1 may contribute to the pathogenesis of interstitial lung disease. PMID: 24107778
    4. Knowledge of the complex expression patterns of BPIF proteins in these regions will allow the use of tractable mouse models of disease to dissect their function. PMID: 22986921
    5. CETP inhibitor torcetrapib promotes reverse cholesterol transport in obese insulin-resistant CETP-ApoB100 transgenic mice PMID: 22212222
    6. a novel gene LPlunc1, a member of BPI/PLUNC gene superfamily, which is asymmetrically expressed in the developing mouse node [LPlunc1 protein] PMID: 14745963

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  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    BPI/LBP/Plunc superfamily, Plunc family
  • 組織特異性：
    Expressed in tongue, lung, thymus, and stomach. Expressed in epithelia of palate, anterior pharynx, trachea and upper bronchi. Expressed in distal tip of papillae in the anterior third of the tongue and in serous cells of von Ebner glands in the posterior
  • 數(shù)據(jù)庫(kù)鏈接：