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  4. Recombinant Phleum pratense Pollen allergen Phl p 5a, partial?

Recombinant Phleum pratense Pollen allergen Phl p 5a, partial?

In Stock
  • 中文名稱：
    Recombinant Phleum pratense Pollen allergen Phl p 5a,partial?
  • 貨號(hào)：
    CSB-EP669216EUQ
  • 規(guī)格：
    ￥2328
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    Pollen allergen Phl p 5a; Allergen Phl p Va; allergen Phl p 5a; Fragment
  • 種屬：
    Phleum pratense (Common timothy)
  • 蛋白長度：
    partial?
  • 來源：
    E.coli
  • 分子量：
    44.5kDa
  • 表達(dá)區(qū)域：
    1-286aa
  • 氨基酸序列
    ADLGYGPATPAAPAAGYTPATPAAPAGADAAGKATTEEQKLIEKINAGFKAALAGAGVQPADKYRTFVATFGPASNKAFAEGLSGEPKGAAESSSKAALTSKLDAAYKLAYKTAEGATPEAKYDAYVATLSEALRIIAGTLEVHAVKPAAEEVKVIPAGELQVIEKVDAAFKVAATAANAAPANDKFTVFEAAFNDEIKASTGGAYESYKFIPALEAAVKQAYAATVATAPEVKYTVFETALKKAITAMSEAQKAAKPAAAATATATAAVGAATGAATAATGGYKV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    N-terminal 6xHis-SUMO-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產(chǎn)品描述：

    The cDNA encoding residues Ala1 to Val286 of the Phleum pratense Pollen allergen Phl p 5a full-length protein was fused with a 6xHis-SUMO-tag at the N-terminus and then expressed in E.coli. The purity of this forming recombinant protein is greater than 90% measured by SDS-PAGE. It migrated to the molecular mass band of approximately 45-56 kDa on the gel under reducing conditions. In addition to generating specific antibodies, this recombinant allergen Phl p 5a protein may find uses in the studies of allergen or allergy.

    Phl p 5a is an isoform of Phl p 5, which is a group 5 allergen from timothy grass and possesses high reactivity. Phl p 5 is highly allergenic and contains two active domains that lead to the production of high IgE levels. When Phl p 5 is recognized by IgE antibodies of almost all grass pollen allergic patients, strong IgE antibody cross-reactivity and T-cell responses responsible for allergy are induced. Sensitized patients develop heavy clinical reactions such as asthma. N. Najafi etc. demonstrated that Bet v 1-Phl p 5 recombinant fusion proteins form IgE-reactive aggregates with reduced allergenic activity.

  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Poa p IX/Phl p VI allergen family