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  4. Recombinant Pig Calpain-1 catalytic subunit (CAPN1), partial

Recombinant Pig Calpain-1 catalytic subunit (CAPN1), partial

  • 中文名稱：
    Recombinant Pig Calpain-1 catalytic subunit(CAPN1) ,partial
  • 貨號：
    CSB-YP004490PI
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Pig Calpain-1 catalytic subunit(CAPN1) ,partial
  • 貨號：
    CSB-EP004490PI
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Pig Calpain-1 catalytic subunit(CAPN1) ,partial
  • 貨號：
    CSB-EP004490PI-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Pig Calpain-1 catalytic subunit(CAPN1) ,partial
  • 貨號：
    CSB-BP004490PI
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Pig Calpain-1 catalytic subunit(CAPN1) ,partial
  • 貨號：
    CSB-MP004490PI
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    CAPN1; Calpain-1 catalytic subunit; EC 3.4.22.52; Calcium-activated neutral proteinase 1; CANP 1; Calpain mu-type; Calpain-1 large subunit; Micromolar-calpain; muCANP
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1.
  • 基因功能參考文獻(xiàn)：
    1. CAPN1 HM535412:g.157T > C showed effect on meat redness. PMID: 21450414
    2. The decreased expression of calpain 1A mRNA during development is highly correlated with muscle protein accumulation in neonatal Sus scrofa. PMID: 19130893
    3. Right ventricular (RV) dysfunction from acute RV pressure overload is, in part, due to activation of calpain, and calpain inhibition would therefore attenuate RV dysfunction. PMID: 18068185
    4. catalytic site amino acid residues 105-133 contained a disulfide bond between Cys(108) and Cys(115) PMID: 18501725
    5. Association of polymorphisms with breed characteristics indicated that the mutations in CAPN1 detected by P4, P6 primers and that resulting in the change of Hinf 1 recognition site may be related to lean meat percentage. PMID: 18550497

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  • 亞細(xì)胞定位：
    Cytoplasm. Cell membrane.
  • 蛋白家族：
    Peptidase C2 family
  • 數(shù)據(jù)庫鏈接：