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  4. Recombinant Pig Sex-determining region Y protein (SRY)

Recombinant Pig Sex-determining region Y protein (SRY)

  • 中文名稱：
    野豬SRY重組蛋白
  • 貨號：
    CSB-YP022699PI
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    野豬SRY重組蛋白
  • 貨號：
    CSB-EP022699PI
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    野豬SRY重組蛋白
  • 貨號：
    CSB-EP022699PI-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    野豬SRY重組蛋白
  • 貨號：
    CSB-BP022699PI
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    野豬SRY重組蛋白
  • 貨號：
    CSB-MP022699PI
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SRY
  • Uniprot No.：
  • 別名：
    SRY; TDFSex-determining region Y protein; Testis-determining factor
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    Full length protein
  • 表達區(qū)域：
    1-236
  • 氨基酸序列
    MVQSYASAMF RVLKADDYSP AAQQQNILAL GKGSSLFPTD NHSSNDGRET RGSGRESGQD RVKRPMNAFI VWSRDQRRKV ALENPQMQNS EISKWLGCKW KMLTEAEKRP FFEEAQRLQA VHRDKYPGYK YRPRRKGERA QNLLPAEAAV LCSQVRVEER MYPFTYTVAK AKCSGTESQL SHSQPMNITS SLLQQEDRCN WTGLCHSRVT STGQIRADLP FHRGLQPGLS HIYFPY
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons.
  • 基因功能參考文獻：
    1. The 4.6 Kb of pig SRY 5' flanking sequences supported reporter transgene expression within the male genital ridge but not within the neural crest. PMID: 16411204
    2. New insights into SRY regulation through identification of 5' conserved sequence are reported. PMID: 18851760
  • 亞細胞定位：
    Nucleus speckle. Cytoplasm. Nucleus.
  • 蛋白家族：
    SRY family
  • 組織特異性：
    Expressed in the genital ridge.
  • 數(shù)據(jù)庫鏈接：