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  4. Recombinant Saccharomyces cerevisiae Protein UTH1 (UTH1)

Recombinant Saccharomyces cerevisiae Protein UTH1 (UTH1)

  • 中文名稱：
    釀酒酵母UTH1重組蛋白
  • 貨號(hào)：
    CSB-YP327496SVG
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母UTH1重組蛋白
  • 貨號(hào)：
    CSB-EP327496SVG
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母UTH1重組蛋白
  • 貨號(hào)：
    CSB-EP327496SVG-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母UTH1重組蛋白
  • 貨號(hào)：
    CSB-BP327496SVG
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母UTH1重組蛋白
  • 貨號(hào)：
    CSB-MP327496SVG
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    UTH1
  • Uniprot No.：
  • 別名：
    UTH1; YKR042WProbable secreted beta-glucosidase UTH1; EC 3.2.1.-; Youth protein 1
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    18-365
  • 氨基酸序列
    APA VHHSDNHHHN DKRAVVTVTQ YVNADGAVVI PAATTATSAA ADGKVESVAA ATTTLSSTAA AATTSAAASS SSSSSSSSSS SSSVGSGDFE DGTISCSDFP SGQGAVSLDW LGLGGWASIM DMNGNTATSC QDGYYCSYAC SPGYAKTQWP SEQPSDGRSV GGLYCKNGKL YRSNTDTNSL CVEGQGSAQA VNKVSGSIAI CGTDYPGSEN MVVPTVVGAG SSQPINVIKE DSYYQWQGKK TSAQYYVNNA GVSVEDGCIW GTEGSGVGNW APVVLGAGYT DGITYLSIIP NPNNKEAPNF NIKIVATDGS TVNGACSYEN GVYSGSGSDG CTVSVTSGSA NFVFY
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in aging, oxidative stress response, and in the regulation of mitochondrial biogenesis. Inactivation of UTH1 increases life span, leads to higher resistance to heat stress and against hydrogen peroxide, and increases sensitivity to the superoxide radical-generating drug paraquat and to copper. Also required for the selective autophagic degradation of mitochondria (mitophagy) in response to nitrogen starvation. Involved in the remodeling of the cell wall during the various phases of yeast culture development and under various environmental conditions and plays a role in septation. Involved in cell sensitivity to boric acid.
  • 基因功能參考文獻(xiàn)：
    1. SUN family proteins Sun4p, Uth1p and Sim1p are secreted from Saccharomyces cerevisiae and produced dependently on oxygen level. PMID: 24040106
    2. re-evaluation of its mitochondrial localization revealed that Uth1 is a protein of the inner mitochondrial membrane that is targeted by a cleavable N-terminal pre-sequence PMID: 23910823
    3. UTH1 is a yeast aging gene that has been identified on the basis of stress resistance and longer life span of mutants. PMID: 15489196
  • 亞細(xì)胞定位：
    Mitochondrion outer membrane; Peripheral membrane protein. Secreted, cell wall. Note=Non-covalently bound to the cell wall (PubMed:11958935).
  • 蛋白家族：
    SUN family
  • 數(shù)據(jù)庫鏈接：

    KEGG: sce:YKR042W

    STRING: 4932.YKR042W