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  4. Recombinant Superoxide dismutase [Mn] 1, mitochondrial (sod-2)

Recombinant Superoxide dismutase [Mn] 1, mitochondrial (sod-2)

  • 中文名稱：
    秀麗隱桿線蟲sod-2重組蛋白
  • 貨號：
    CSB-YP330058CXY
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲sod-2重組蛋白
  • 貨號：
    CSB-EP330058CXY
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲sod-2重組蛋白
  • 貨號：
    CSB-EP330058CXY-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲sod-2重組蛋白
  • 貨號：
    CSB-BP330058CXY
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲sod-2重組蛋白
  • 貨號：
    CSB-MP330058CXY
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    sod-2
  • Uniprot No.：
  • 別名：
    sod-2; sdm-1; F10D11.1; Superoxide dismutase [Mn] 1; mitochondrial; EC 1.15.1.1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    25-221
  • 氨基酸序列
    KHSLPD LPYDYADLEP VISHEIMQLH HQKHHATYVN NLNQIEEKLH EAVSKGNVKE AIALQPALKF NGGGHINHSI FWTNLAKDGG EPSAELLTAI KSDFGSLDNL QKQLSASTVA VQGSGWGWLG YCPKGKILKV ATCANQDPLE ATTGLVPLFG IDVWEHAYYL QYKNVRPDYV NAIWKIANWK NVSERFAKAQ Q
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
  • 基因功能參考文獻：
    1. results suggest that SOD-2 plays an important role in the sperm activation of C. elegans by producing H2O2 as an activator of pseudopod extension PMID: 28724632
    2. Interactions of the mitochondrial superoxide dismutases (mtSODs): SOD-2 and SOD-3, are reported. PMID: 23895727
    3. Damage levels in the mtDNA of SOD mutants are not significantly different from those in wild-type animals, i.e. even the total loss of mitochondrial SOD did not significantly increase oxidative damage to mtDNA. PMID: 21611128
    4. identify and analyze the sequence and structure characteristics that ensure the cofactor specificities and the oligomerization modes PMID: 17912757
    5. although several long-lived mutants of Caenorhabditis elegans have increased SOD levels, this phenomenon does not correlate with life span or growth rate. PMID: 18073424
    6. increased oxidative stress caused by deletion of sod genes does not result in decreased lifespan in C. elegans and that deletion of sod-2 extends worm lifespan by altering mitochondrial function PMID: 19197346

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  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Iron/manganese superoxide dismutase family
  • 數據庫鏈接：

    KEGG: cel:CELE_F10D11.1

    STRING: 6239.F10D11.1.2

    UniGene: Cel.112