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  4. Recombinant Gamma-secretase subunit pen-2 (pen-2)

Recombinant Gamma-secretase subunit pen-2 (pen-2)

  • 中文名稱：
    秀麗隱桿線蟲pen-2重組蛋白
  • 貨號：
    CSB-CF880030CXY
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
    pen-2
  • Uniprot No.：
  • 別名：
    pen-2; T28D6.9; Gamma-secretase subunit pen-2; Presenilin enhancer protein 2
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-101
  • 氨基酸序列
    MDISKLTDVKKVDLCKKYFLIGACFLPLVWIVNTFWFFSDAFCKPINAHRRQIRKYVIAS IVGSIFWIIVLSAWEIFFQHYRAQGLVWTDFLTFVFPTGRV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch (glp-1 or lin-12). It may represent a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Predominantly located in the endoplasmic reticulum and Golgi region.
  • 蛋白家族：
    PEN-2 family
  • 組織特異性：
    Expressed from 100-cell stage in most somatic tissues, including neurons, muscle, intestine and developing vulva. Little or not expressed in early embryos.
  • 數(shù)據(jù)庫鏈接：

    KEGG: cel:CELE_T28D6.9

    STRING: 6239.T28D6.9

    UniGene: Cel.9963