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  4. Recombinant Human Taste receptor type 2 member 39 (TAS2R39)

Recombinant Human Taste receptor type 2 member 39 (TAS2R39)

  • 中文名稱：
    人TAS2R39重組蛋白
  • 貨號：
    CSB-CF023156HU
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
  • Uniprot No.：
  • 別名：
    TAS2R39; Taste receptor type 2 member 39; T2R39; Taste receptor type 2 member 57; T2R57
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full length protein
  • 表達區(qū)域：
    1-338
  • 氨基酸序列
    MLGRCFPPDTKEKQQLRMTKLCDPAESELSPFLITLILAVLLAEYLIGIIANGFIMAIHA AEWVQNKAVSTSGRILVFLSVSRIALQSLMMLEITISSTSLSFYSEDAVYYAFKISFIFL NFCSLWFAAWLSFFYFVKIANFSYPLFLKLRWRITGLIPWLLWLSVFISFSHSMFCINIC TVYCNNSFPIHSSNSTKKTYLSEINVVGLAFFFNLGIVTPLIMFILTATLLILSLKRHTL HMGSNATGSNDPSMEAHMGAIKAISYFLILYIFNAVALFIYLSNMFDINSLWNNLCQIIM AAYPASHSILLIQDNPGLRRAWKRLQLRLHLYPKEWTL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
  • 基因功能參考文獻：
    1. hTAS2R39 is the primary receptor for the bitterness of theaflavins PMID: 25273142
    2. TAS2R14 and TAS2R39 were activated by isoflavones and other isoflavonoids. PMID: 21942422
    3. Human bitter taste receptors hTAS2R8 and hTAS2R39 display differential functions to recognize bitter peptides. PMID: 21670512
    4. these results suggest the participation of hTAS2R39 in the detection of catechins in humans. PMID: 21272567
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor T2R family
  • 組織特異性：
    Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18886

    KEGG: hsa:259285

    STRING: 9606.ENSP00000405095

    UniGene: Hs.553660